Alvarez-Buylla Elena R, Benítez Mariana, Corvera-Poiré Adriana, Chaos Cador Alvaro, de Folter Stefan, Gamboa de Buen Alicia, Garay-Arroyo Adriana, García-Ponce Berenice, Jaimes-Miranda Fabiola, Pérez-Ruiz Rigoberto V, Piñeyro-Nelson Alma, Sánchez-Corrales Yara E
Arabidopsis Book. 2010;8:e0127. doi: 10.1199/tab.0127. Epub 2010 Mar 23.
Flowers are the most complex structures of plants. Studies of Arabidopsis thaliana, which has typical eudicot flowers, have been fundamental in advancing the structural and molecular understanding of flower development. The main processes and stages of Arabidopsis flower development are summarized to provide a framework in which to interpret the detailed molecular genetic studies of genes assigned functions during flower development and is extended to recent genomics studies uncovering the key regulatory modules involved. Computational models have been used to study the concerted action and dynamics of the gene regulatory module that underlies patterning of the Arabidopsis inflorescence meristem and specification of the primordial cell types during early stages of flower development. This includes the gene combinations that specify sepal, petal, stamen and carpel identity, and genes that interact with them. As a dynamic gene regulatory network this module has been shown to converge to stable multigenic profiles that depend upon the overall network topology and are thus robust, which can explain the canalization of flower organ determination and the overall conservation of the basic flower plan among eudicots. Comparative and evolutionary approaches derived from Arabidopsis studies pave the way to studying the molecular basis of diverse floral morphologies.
花是植物最复杂的结构。对具有典型双子叶植物花的拟南芥的研究，在推进对花发育的结构和分子理解方面具有基础性作用。总结了拟南芥花发育的主要过程和阶段，以提供一个框架，用于解释在花发育过程中被赋予功能的基因的详细分子遗传学研究，并扩展到揭示所涉及的关键调控模块的近期基因组学研究。计算模型已被用于研究基因调控模块的协同作用和动态变化，该模块是拟南芥花序分生组织模式形成以及花发育早期原基细胞类型特化的基础。这包括指定萼片、花瓣、雄蕊和心皮身份的基因组合，以及与它们相互作用的基因。作为一个动态基因调控网络，该模块已被证明会收敛到稳定的多基因谱，这些谱取决于整体网络拓扑结构，因此具有稳健性，这可以解释花器官决定的定向进化以及双子叶植物基本花型的整体保守性。源自拟南芥研究的比较和进化方法为研究多样花形态的分子基础铺平了道路。
