Health Innovations Research Institute & School of Applied Sciences, RMIT University, School Applied Sciences, Building 3, Bowen Street Melbourne VIC 3001, Australia.
Mini Rev Med Chem. 2012 May;12(5):380-7. doi: 10.2174/138955712800493906.
Evidence for the medicinal and health benefits of polyphenols in green tea for the prevention of chronic diseases such as heart disease, various types of cancer and neurodegenerative diseases is advancing. Their in vivo effectiveness and molecular mechanisms are difficult to elucidate and remain a challenging task. We review the redox responsiveness and amyloid protein perturbation biophysical properties of the major green tea polyphenol constituent (-)- epigallocatechin-3-gallate [EGCG].
证据表明，绿茶中的多酚类化合物具有药用和保健功效，可预防心脏病、各类癌症和神经退行性疾病等慢性病。然而，其体内功效和分子机制尚难以阐明，仍是一项具有挑战性的任务。我们综述了主要的绿茶多酚成分（-）-表没食子儿茶素-3-没食子酸酯[EGCG]的氧化还原响应性和对淀粉样蛋白扰动的生物物理特性。
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