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绿茶多酚的健康益处及其分子机制的研究进展。

Recent Advances in the Understanding of the Health Benefits and Molecular Mechanisms Associated with Green Tea Polyphenols.

机构信息

Department of Food Science , University of Guelph , Guelph , Ontario N1G 2W1 , Canada.

Key Lab of Meat Processing and Quality Control, College of Food Science and Technology , Nanjing Agricultural University , Nanjing , Jiangsu 210095 , China.

出版信息

J Agric Food Chem. 2019 Jan 30;67(4):1029-1043. doi: 10.1021/acs.jafc.8b06146. Epub 2019 Jan 17.

DOI:10.1021/acs.jafc.8b06146
PMID:30653316
Abstract

Tea, leaf, or bud from the plant Camellia sinensis, make up some of the beverages popularly consumed in different parts of the world as green tea, oolong tea, or black tea. More particularly, as a nonfermented tea, green tea has gained more renown because of the significant health benefits assigned to its rich content in polyphenols. As a main constituent, green tea polyphenols were documented for their antioxidant, anti-inflammation, anticancer, anticardiovascular, antimicrobial, antihyperglycemic, and antiobesity properties. Recent reports demonstrate that green tea may exert a positive effect on the reduction of medical chronic conditions such as cardiovascular disease, cancer, Alzheimer's disease, Parkinson's disease, and diabetes. The health benefits of green teas, in particular EGCG, are widely investigated, and these effects are known to be primarily associated with the structure and compositions of its polyphenols. This Review focuses on the diverse constituents of green tea polyphenols and their molecular mechanisms from the perspective of their potential therapeutic function. Recent advances of green tea polyphenols on their bioavailability, bioaccessibility, and microbiota were also summarized in this article. Dietary supplementation with green tea represents an attractive alternative toward promoting human health.

摘要

茶叶,来自茶树(Camellia sinensis)的叶子或芽,构成了一些在世界不同地区流行的饮料,如绿茶、乌龙茶或红茶。更具体地说,作为一种未发酵的茶,绿茶因其富含多酚而具有显著的健康益处而备受推崇。作为主要成分,绿茶多酚因其抗氧化、抗炎、抗癌、抗心血管、抗菌、抗高血糖和抗肥胖特性而被记录在案。最近的报告表明,绿茶可能对降低心血管疾病、癌症、阿尔茨海默病、帕金森病和糖尿病等医学慢性病有积极影响。绿茶,特别是 EGCG 的健康益处得到了广泛的研究,这些作用主要与它的多酚的结构和组成有关。本综述从潜在治疗功能的角度,重点关注绿茶多酚的多种成分及其分子机制。本文还总结了绿茶多酚在生物利用度、生物可及性和微生物群方面的最新进展。食用绿茶补充剂是促进人类健康的一种有吸引力的选择。

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