College of Chemistry, Liaoning University, Shenyang 110036, China.
Nat Prod Res. 2013;27(1):32-6. doi: 10.1080/14786419.2012.658796. Epub 2012 Feb 3.
In this article, we have focused on the application of non-traditional separation approach, the host-guest inclusion method, into the separation of the active component patchouli alcohol from the essential oil of Cablin potchouli Herb. The host molecule 1,1,6,6-tetraphenylhexa-2,4-diyne-1,6-diol (A) was used to selectively recognise the guest molecule patchouli alcohol (B) in the essential oil of Pogostemon cablin (Blanco) Benth through two strong hydrogen bonding. The inclusion compound was structurally determined by the single crystal X-ray diffraction. The separation effect was examined by gas chromatography for the whole essential oil and the inclusion compound, showing that the inclusion crystalline method is simple, rapid and effective for the separation of patchouli alcohol from the essential oil of C. potchouli Herb.
在本文中，我们专注于非传统分离方法——主体-客体包合方法在从广藿香精油中分离有效成分广藿香醇中的应用。主体分子 1,1,6,6-四苯基-2,4-二炔-1,6-二醇（A）通过两个强氢键选择性识别广藿香精油（B）中的客体分子广藿香醇（B）。包合物通过单晶 X 射线衍射进行结构测定。通过气相色谱法对全精油和包合物进行分离效果检查，表明包合结晶法是一种简单、快速、有效的从广藿香精油中分离广藿香醇的方法。
