Department of Surgery, Instituto Nacional de la Nutrición Salvador Zubirán, Mexico City, Mexico.
Best Pract Res Clin Endocrinol Metab. 2012 Feb;26(1):97-103. doi: 10.1016/j.beem.2011.06.005.
Pancreatic incidentalomas are defined as asymptomatic pancreatic lesions, discovered incidentally by imaging for an unrelated indication. They are being discovered with increasing frequency as the use of high quality cross sectional imaging is becoming more widespread. These lesions cover a wide spectrum of pathology from benign simple cysts through potentially malignant lesions such as intraductal papillary mucinous neoplasia, to frankly malignant adenocarcinoma. In this article we outline the incidence, imaging characteristics and natural history of the various incidental lesions with emphasis to neuroendocrine tumors. A diagnostic approach is also suggested, including the rational use of further imaging, serum biochemistry and the utility of ultrasound guided aspiration of cyst fluid if present. We examine several proposed classification systems and discuss the role of surgery, surveillance and prognosis.
胰腺偶发瘤是指无症状的胰腺病变,在因其他无关原因进行影像学检查时偶然发现。随着高质量的横断面成像的应用越来越广泛,它们的发现频率也越来越高。这些病变涵盖了从良性单纯囊肿到具有潜在恶性的病变(如导管内乳头状黏液性肿瘤),再到明显恶性的腺癌等广泛的病理学范围。本文概述了各种偶发病变的发生率、影像学特征和自然病史,重点介绍了神经内分泌肿瘤。还提出了一种诊断方法,包括合理使用进一步的影像学检查、血清生物化学检查,以及在存在囊性液体时超声引导抽吸囊液的应用。我们还研究了几种提出的分类系统,并讨论了手术、监测和预后的作用。