Boonsawat W, Boonma P, Tangdajahiran T, Paupermpoonsiri S, Wongpratoom W, Romphryk A
Department of Medicine, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Thailand.
J Med Assoc Thai. 1990 Jun;73(6):345-52.
A prospective study of community-acquired pneumonia in adults at Srinagarind Hospital, Khon kaen University was conducted from September 1987 to August 1988. Laboratory specimens were tested for bacterial and mycoplasmal culture, CIE for pneumococcal antigen and serological data for mycoplasma and P. pseudomallei. The results supported by clinical data were evaluated. We could identify the pathogens from 62 of 113 cases (55%). P. pseudomallei was the most frequent etiologic agent (32%) and S. pneumoniae was the second (27%). Overall mortality was 21 per cent and it was high in cases with bacteremia and pneumonia due to P. pseudomallei. Sixty-six per cent of the patients had associated diseases. Diabetes mellitus, chronic renal failure and renal calculi were commonly found in patients with pneumonia due to P. pseudomallei. The results of this study showed the relatively high prevalence of P. pseudomallei pneumonia in our region which was different from other reports.
1987年9月至1988年8月,孔敬大学诗里拉吉医院对成人社区获得性肺炎进行了一项前瞻性研究。对实验室标本进行了细菌和支原体培养检测、肺炎球菌抗原的对流免疫电泳检测以及支原体和类鼻疽杆菌的血清学数据检测。结合临床数据对结果进行了评估。我们在113例病例中的62例(55%)中鉴定出了病原体。类鼻疽杆菌是最常见的病原体(32%),肺炎链球菌位居第二(27%)。总体死亡率为21%,在菌血症和由类鼻疽杆菌引起的肺炎病例中死亡率较高。66%的患者患有相关疾病。糖尿病、慢性肾衰竭和肾结石在由类鼻疽杆菌引起的肺炎患者中较为常见。本研究结果表明,我们所在地区类鼻疽杆菌肺炎的患病率相对较高,这与其他报告不同。