Petras Melissa L, Dunbar Nancy M, Filiano James J, Braga Matthew S, Chobanian Michael C, Szczepiorkowski Zbigniew M
Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
J Clin Apher. 2012;27(4):212-4. doi: 10.1002/jca.21208. Epub 2012 Feb 3.
Streptococcus pneumoniae-associated hemolytic uremic syndrome (pHUS) is an atypical form of HUS associated with microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. Although less common than diarrhea-associated HUS, incidence appears to be increasing. We report a case of a child with pHUS who underwent a course of therapeutic plasma exchange (TPE) and had complete recovery. This report adds to the existing literature supporting TPE in cases of pHUS.
肺炎链球菌相关的溶血性尿毒症综合征(pHUS)是溶血性尿毒症综合征的一种非典型形式,与微血管病性溶血性贫血、血小板减少症和急性肾衰竭相关。尽管不如腹泻相关的溶血性尿毒症综合征常见,但发病率似乎在上升。我们报告一例患有pHUS的儿童,该患儿接受了一个疗程的治疗性血浆置换(TPE)并完全康复。本报告补充了现有文献中支持在pHUS病例中使用TPE的内容。