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肺炎链球菌相关溶血尿毒综合征的治疗性血浆置换:一例报告

Therapeutic plasma exchange in Streptococcus pneumoniae-associated hemolytic uremic syndrome: a case report.

作者信息

Petras Melissa L, Dunbar Nancy M, Filiano James J, Braga Matthew S, Chobanian Michael C, Szczepiorkowski Zbigniew M

机构信息

Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.

出版信息

J Clin Apher. 2012;27(4):212-4. doi: 10.1002/jca.21208. Epub 2012 Feb 3.

Abstract

Streptococcus pneumoniae-associated hemolytic uremic syndrome (pHUS) is an atypical form of HUS associated with microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. Although less common than diarrhea-associated HUS, incidence appears to be increasing. We report a case of a child with pHUS who underwent a course of therapeutic plasma exchange (TPE) and had complete recovery. This report adds to the existing literature supporting TPE in cases of pHUS.

摘要

肺炎链球菌相关的溶血性尿毒症综合征(pHUS)是溶血性尿毒症综合征的一种非典型形式,与微血管病性溶血性贫血、血小板减少症和急性肾衰竭相关。尽管不如腹泻相关的溶血性尿毒症综合征常见,但发病率似乎在上升。我们报告一例患有pHUS的儿童,该患儿接受了一个疗程的治疗性血浆置换(TPE)并完全康复。本报告补充了现有文献中支持在pHUS病例中使用TPE的内容。

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