铜（I）催化的硼酸酯（11）C 羧化反应：一种快速方便的（11）C 标记羧酸、酯和酰胺的方法。
Cu(I)-catalyzed (11)C carboxylation of boronic acid esters: a rapid and convenient entry to (11)C-labeled carboxylic acids, esters, and amides.
机构信息
Wolfson Brain Imaging Centre, University of Cambridge, Addenbrooke's Hospital, UK.
出版信息
Angew Chem Int Ed Engl. 2012 Mar 12;51(11):2698-702. doi: 10.1002/anie.201107263. Epub 2012 Feb 3.
Abstract
Rapid and direct: the carboxylation of boronic acid esters with (11)CO(2) provides [(11)C]carboxylic acids as a convenient entry into [(11)C]esters and [(11)C]amides. This conversion of boronates is tolerant to diverse functional groups (e.g., halo, nitro, or carbonyl).
摘要
快速直接
（11）CO2 与硼酸酯的羧化反应为制备 [(11)C]羧酸提供了便捷的途径，继而可以转化为 [(11)C]酯和 [(11)C]酰胺。硼酸酯的这种转化对各种功能基团（例如卤素、硝基或羰基）具有耐受性。
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