College of Nanoscale Science and Engineering (CNSE), University at Albany, Albany, NY, USA.
Sci Prog. 2011;94(Pt 4):431-50. doi: 10.3184/003685011X13201828216868.
Modern microbiological research has increasingly focused on the interactions between bacterial cells and the surfaces that they inhabit. To this end, microfluidic devices have played a large role in enabling research of cell-surface interactions, especially surface attachment and biofilm formation. This review provides background on microfluidic devices and their use in biological systems, as well specific examples from current literature. Methods to observe and interrogate cells within microfluidic devices are described, as well as the analytical techniques that are used to collect these data.
现代微生物学研究越来越关注细菌细胞与它们栖息的表面之间的相互作用。为此，微流控设备在研究细胞-表面相互作用方面发挥了重要作用，特别是在表面附着和生物膜形成方面。本文综述了微流控设备及其在生物系统中的应用，并提供了当前文献中的具体实例。描述了在微流控设备中观察和询问细胞的方法，以及用于收集这些数据的分析技术。
