意大利普利亚地区人博卡病毒的血清流行病学研究。
Seroepidemiology of human bocavirus in Apulia, Italy.
机构信息
Laboratory of Hygiene, Department of Biological and Environmental Sciences and Technologies, Faculty of Sciences, University of Salento, Lecce Institute of Clinical Physiology, National Research Council, Lecce, Italy.
出版信息
Clin Microbiol Infect. 2012 Apr;18(4):E74-6. doi: 10.1111/j.1469-0691.2011.03756.x. Epub 2012 Feb 6.
A serological survey was performed to determine the prevalence of antibodies against human bocavirus in an Apulian population. Anti-hBoV IgG antibodies were analysed in 1206 inhabitants (age range, 1month-84years) using a standardized ELISA test based on the use of recombinant hBoV VP2 virus-like particles. In total, 1075 (89.1%) of 1206 participants (mean age 32±24.8years) displayed anti-hBoV-IgG. The seroprevalence increased significantly (p<0.0001) in children from 2-4years (64.2%) to 5-9years (96.4%). A similar trend was observed in both male and female subjects. In conclusion, our results show that hBoV infection is common in this population, especially in children.
进行了一项血清学调查，以确定在普利亚人群中抗人类博卡病毒的抗体流行率。使用基于重组 hBoV VP2 病毒样颗粒的标准化 ELISA 试验，分析了 1206 名居民（年龄范围为 1 个月至 84 岁）中的抗 hBoV-IgG 抗体。在 1206 名参与者中（平均年龄为 32±24.8 岁），有 1075 名（89.1%）显示出抗 hBoV-IgG。儿童（2-4 岁为 64.2%，5-9 岁为 96.4%）的血清阳性率显著增加（p<0.0001）。在男性和女性受试者中均观察到类似的趋势。总之，我们的结果表明，在该人群中 hBoV 感染很常见，尤其是在儿童中。
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