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坦桑尼亚一家三级医院慢性化脓性中耳炎的患病率及病原体

Prevalence and etiological agents for chronic suppurative otitis media in a tertiary hospital in Tanzania.

作者信息

Abraham Zephania Saitabau, Ntunaguzi Daudi, Kahinga Aveline Aloyce, Mapondella Kassim Babu, Massawe Enica Richard, Nkuwi Emmanuel James, Nkya Aslam

机构信息

Department of Surgery, University of Dodoma, College of Health and Allied Sciences, Box 259, Dodoma, Tanzania.

Department of Otorhinolaryngology, Muhimbili University of Health and Allied Sciences, Box 65001, Dar es Salaam, Tanzania.

出版信息

BMC Res Notes. 2019 Jul 17;12(1):429. doi: 10.1186/s13104-019-4483-x.

DOI:10.1186/s13104-019-4483-x
PMID:31315659
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6637475/
Abstract

OBJECTIVE

Chronic suppurative otitis media is among the most common otological condition reported in otorhinolaryngology practice commonly attributing to preventable hearing loss. The aim of this study was to determine the prevalence and etiological agents for chronic suppurative otitis media in our department.

RESULTS

A total of 5591 patients were recruited in this study and only 79 (1.4%) had chronic suppurative otitis media. A male preponderance 43 (54.4%) was noted in this study and the left ear (58.2%) was more commonly affected compared to the right ear. Central perforation was the commonest pattern of presentation and was reported in 53% of cases though none had attic perforation. Of the 81 processed ear swabs, microbial growth was seen in majority 80 (98.8%) whilst one sample showed no microbial growth whereas 52.5% had polymicrobial growth. Among the isolates, most were gram negative species accounting for 59.7% while gram positive bacteria accounted for 25.6% and fungi accounted for 14.7%. Most of these isolates were facultative anaerobes. Klebsiella pneumoniae (20.2%) was the commonest isolates while Escherichia coli and Pseudomonas aeruginosa were equally least isolated (10.9%). Tested isolates were most sensitive to Ciprofloxacin, Gentamycin, Ceftriaxone and Amikacin and least sensitive to Amoxicillin/clavulanic acid and Ampicillin.

摘要

目的

慢性化脓性中耳炎是耳鼻咽喉科临床最常见的耳部疾病之一,常导致可预防性听力损失。本研究旨在确定我科慢性化脓性中耳炎的患病率及病因。

结果

本研究共纳入5591例患者,仅79例(1.4%)患有慢性化脓性中耳炎。本研究中男性占优势,有43例(54.4%),且左耳(58.2%)比右耳更常受累。中央性穿孔是最常见的表现形式,53%的病例有此表现,不过没有上鼓室穿孔的病例。在81份送检的耳拭子中,大多数80份(98.8%)有微生物生长,1份样本无微生物生长,52.5%有多种微生物生长。在分离出的菌株中,大多数是革兰阴性菌,占59.7%,革兰阳性菌占25.6%,真菌占14.7%。这些分离菌株大多是兼性厌氧菌。肺炎克雷伯菌(20.2%)是最常见的分离菌株,而大肠杆菌和铜绿假单胞菌的分离率同样最低(10.9%)。检测的分离菌株对环丙沙星、庆大霉素、头孢曲松和阿米卡星最敏感,对阿莫西林/克拉维酸和氨苄西林最不敏感。

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