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神经性厌食症伴肢端肥大样特征、手足发绀症和雷诺现象的发作以及冻疮恶化。

Anorexia nervosa associated with acromegaloid features, onset of acrocyanosis and Raynaud's phenomenon and worsening of chilblains.

作者信息

Rustin M H, Foreman J C, Dowd P M

机构信息

Department of Dermatology, University College and Middlesex School of Medicine, Middlesex Hospital, London.

出版信息

J R Soc Med. 1990 Aug;83(8):495-6. doi: 10.1177/014107689008300807.

DOI:10.1177/014107689008300807
PMID:2231576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1292774/
Abstract

Patients with anorexia nervosa may develop many physical and endocrinological complications. We wish to report two patients who developed soft tissue swelling of their hands and worsening of their peripheral vascular disease, evidenced by the appearance of acrocyanosis and Raynaud's phenomenon and more severe perniosis, following the onset of their anorexia nervosa.

摘要

神经性厌食症患者可能会出现许多身体和内分泌方面的并发症。我们希望报告两名患者,他们在神经性厌食症发病后,手部出现软组织肿胀,外周血管疾病恶化,表现为手足发绀症和雷诺现象的出现以及更严重的冻疮。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afdd/1292774/4a3acabc9c14/jrsocmed00133-0019-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afdd/1292774/388e3db330bf/jrsocmed00133-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afdd/1292774/c30da95c676a/jrsocmed00133-0019-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afdd/1292774/4a3acabc9c14/jrsocmed00133-0019-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afdd/1292774/388e3db330bf/jrsocmed00133-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afdd/1292774/c30da95c676a/jrsocmed00133-0019-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afdd/1292774/4a3acabc9c14/jrsocmed00133-0019-c.jpg

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Anorexia nervosa associated with acromegaloid features, onset of acrocyanosis and Raynaud's phenomenon and worsening of chilblains.神经性厌食症伴肢端肥大样特征、手足发绀症和雷诺现象的发作以及冻疮恶化。
J R Soc Med. 1990 Aug;83(8):495-6. doi: 10.1177/014107689008300807.
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Case did not consider all potential causes of chilblains.凯斯没有考虑到冻疮的所有潜在病因。
CMAJ. 2020 Sep 8;192(36):E1046. doi: 10.1503/cmaj.76376.
3
Acrocyanosis: the Flying Dutchman.肢端发绀:飞荷兰人。

本文引用的文献

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Increased cutaneous vasoreactivity to cold in anorexia nervosa.
Clin Sci (Lond). 1981 Nov;61(5):559-67. doi: 10.1042/cs0610559.
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A unique growth factor in patients with acromegaloidism.
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The endocrinology of anorexia nervosa and bulimia nervosa.神经性厌食症和神经性贪食症的内分泌学
Endocrinol Metab Clin North Am. 1988 Mar;17(1):195-212.
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Vasc Med. 2011 Aug;16(4):288-301. doi: 10.1177/1358863X11398519. Epub 2011 Mar 22.
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Pernio (chilblains).冻疮。
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Tolerability and efficacy of aripiprazole in a case of psychotic anorexia nervosa comorbid with epilepsy and chronic renal failure.阿立哌唑在一例合并癫痫和慢性肾衰竭的神经性厌食症精神病患者中的耐受性和疗效。
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Phobic memory and somatic vulnerabilities in anorexia nervosa: a necessary unity?神经性厌食症中的恐惧记忆与躯体易损性:一种必要的统一?
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Serum levels of the low molecular weight form of insulin-like growth factor binding protein in healthy subjects and patients with growth hormone deficiency, acromegaly and anorexia nervosa.健康受试者以及生长激素缺乏症、肢端肥大症和神经性厌食症患者血清中低分子量胰岛素样生长因子结合蛋白的水平。
Acta Endocrinol (Copenh). 1988 Jul;118(3):321-6. doi: 10.1530/acta.0.1180321.