High-penetration optical coherence tomography with enhanced depth imaging of polypoidal choroidal vasculopathy.

A combination of high-penetration spectral-domain optical coherence tomography (central wavelength: 1,020 nm) and an enhanced depth imaging protocol (HP-EDI-OCT) was used to evaluate 5 eyes of 5 patients with polypoidal choroidal vasculopathy (PCV). In all eyes, HP-EDI-OCT provided high-contrast images of PCV lesions in the subretinal pigment epithelium (sub-RPE). In the space between the RPE line and Bruch's membrane, various PCV lesions, including vascular networks, polypoidal lesions, and sub-RPE hemorrhage, were clearly identified. The chorioscleral interface was clearly observed, and the entire structure of the choroid was readily identified. Thus, HP-EDI-OCT was useful for evaluating sub-RPE lesions of PCV.