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具有增强深度成像的高穿透性光学相干断层扫描在息肉样脉络膜血管病变中的应用

High-penetration optical coherence tomography with enhanced depth imaging of polypoidal choroidal vasculopathy.

作者信息

Nagase Satoko, Miura Masahiro, Makita Shuichi, Iwasaki Takuya, Goto Hiroshi, Yasuno Yoshiaki

机构信息

Department of Ophthalmology, Tokyo Medical University, Ibaraki Medical Center, Ami, Japan.

出版信息

Ophthalmic Surg Lasers Imaging. 2012 Feb 9;43 Online:e5-9. doi: 10.3928/15428877-20120130-02.

DOI:10.3928/15428877-20120130-02
PMID:22320832
Abstract

A combination of high-penetration spectral-domain optical coherence tomography (central wavelength: 1,020 nm) and an enhanced depth imaging protocol (HP-EDI-OCT) was used to evaluate 5 eyes of 5 patients with polypoidal choroidal vasculopathy (PCV). In all eyes, HP-EDI-OCT provided high-contrast images of PCV lesions in the subretinal pigment epithelium (sub-RPE). In the space between the RPE line and Bruch's membrane, various PCV lesions, including vascular networks, polypoidal lesions, and sub-RPE hemorrhage, were clearly identified. The chorioscleral interface was clearly observed, and the entire structure of the choroid was readily identified. Thus, HP-EDI-OCT was useful for evaluating sub-RPE lesions of PCV.

摘要

采用高穿透光谱域光学相干断层扫描(中心波长:1020 nm)与增强深度成像协议相结合的方法(HP-EDI-OCT)对5例息肉样脉络膜血管病变(PCV)患者的5只眼进行评估。在所有眼中,HP-EDI-OCT均能提供视网膜色素上皮下(sub-RPE)PCV病变的高对比度图像。在视网膜色素上皮(RPE)线与布鲁赫膜之间的间隙中,能够清晰识别出各种PCV病变,包括血管网络、息肉样病变和RPE下出血。脉络膜巩膜界面清晰可见,脉络膜的整体结构也易于识别。因此,HP-EDI-OCT有助于评估PCV的RPE下病变。

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引用本文的文献

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Polypoidal Choroidal Vasculopathy in Asians.亚洲人的息肉样脉络膜血管病变
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The noninvasive retro-mode imaging modality of confocal scanning laser ophthalmoscopy in polypoidal choroidal vasculopathy: a preliminary application.共焦扫描激光眼底镜在息肉样脉络膜血管病变中的非侵入性逆行模式成像模态:初步应用
PLoS One. 2013 Sep 18;8(9):e75711. doi: 10.1371/journal.pone.0075711. eCollection 2013.
3
In-vivo investigation of laser-induced choroidal neovascularization in rat using spectral-domain optical coherence tomography (SD-OCT).
利用频域光学相干断层扫描(SD-OCT)对大鼠激光诱导脉络膜新生血管的体内研究。
Graefes Arch Clin Exp Ophthalmol. 2013 May;251(5):1293-301. doi: 10.1007/s00417-012-2185-3. Epub 2012 Nov 1.