Fazeli Zeinab, Pourhoseingholi Mohamad Amin, Pourhoseingholi Asma, Vahedi Mohsen, Zali Mohammad Reza
Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Asian Pac J Cancer Prev. 2011;12(10):2763-6.
Oral cavity cancer is the eighth most frequent cancer among men in the world. Its incidence varies widely geographically and two-thirds of the incident cases are diagnosed in developing countries. The aim of this study was to present the mortality trends from this cancer for Iranian population during a period of almost a decade, in order to provide update information regarding time trends for this cancer.
We analyzed National death Statistics reported by the Iranian Ministry of Health and Medical Education from 1995 to 2004, stratified by age group, sex, and cause of death. Oral cavity cancer [ICD-10; C00-08] was assessed for annual mortality rates/100,000, overall, by sex and by age group (<15, 15-49 and ≥ 50 years of age) and age standardized rates (ASR) were calculated.
The age standardized mortality rate of oral cavity cancer increased dramatically during these years from 0.09 per 100,000 in 1995 to 0.59 per 100,000 in 2002. However, a sharp decrease was observed from 2002 to 2004. Moreover the mortality of oral cavity cancer was higher for males except from 2000-2002 during which the rate of female's death was close to male's. Age specific rates for oral cavity cancer indicated higher mortality rate for older age.
In conclusion, this study provides comprehensive projection for burden of death due to oral cavity cancer, indicating that the trend of its mortality was increased in recent decade and then would be leveled off. While the burden of oral cavity cancer in Iran is lower than other Asian countries, further studies are required to establish risk factors or modifiers for this cancer in Iranian population in order to decrease its incidence and mortality.
口腔癌是全球男性中第八大常见癌症。其发病率在地理上差异很大，三分之二的发病病例在发展中国家被诊断出来。本研究的目的是呈现近十年来伊朗人口中这种癌症的死亡率趋势，以便提供有关该癌症时间趋势的最新信息。
我们分析了伊朗卫生和医学教育部报告的1995年至2004年的国家死亡统计数据，按年龄组、性别和死因进行分层。评估了口腔癌[国际疾病分类第10版；C00 - 08]的年死亡率/10万，总体上、按性别和年龄组（<15岁、15 - 49岁和≥50岁）进行评估，并计算年龄标准化率（ASR）。
这些年口腔癌的年龄标准化死亡率从1995年的每10万0.09急剧上升至2002年的每10万0.59。然而，2002年至2004年观察到急剧下降。此外，除了2000 - 2002年女性死亡率接近男性外，口腔癌男性死亡率更高。口腔癌的年龄别死亡率表明老年人群死亡率更高。
总之，本研究提供了口腔癌死亡负担的全面预测，表明其死亡率在近十年呈上升趋势，然后趋于平稳。虽然伊朗口腔癌的负担低于其他亚洲国家，但仍需要进一步研究确定伊朗人群中该癌症的危险因素或影响因素，以降低其发病率和死亡率。
