列宁格勒地区儿童散发性无菌性脑膜炎的病因

Etiology of sporadic aseptic meningitis in children in the Leningrad area.

作者信息

Galko N V, Vashukova S S, Dadiomova M A, Nool L A

出版信息

Scand J Infect Dis. 1979;11(2):173-4. doi: 10.3109/inf.1979.11.issue-2.15.

DOI:10.3109/inf.1979.11.issue-2.15

Abstract

The etiology of sporadic aseptic meningitis among children in the Leningrad area in 1974 was studied. 184 patients and 284 healthy children of the same age groups were studied; altogether 540 stool specimens and 99 cerebrospinal fluid specimens were collected for virus isolations and 162 pairs of sera for virus antibody assays. Mumps virus infection was the etiology of the disease only in 5% of cases. The main etiological role of enteroviruses was proved. Strains most often associated with disease were echoviruses 6 and 14, coxsackievirus A9 and nontypable strains. Additional strains isolated were echoviruses 2, 9, 11 and 20.

摘要

对1974年列宁格勒地区儿童散发性无菌性脑膜炎的病因进行了研究。研究了184例患者和284名同年龄组的健康儿童；共采集了540份粪便标本和99份脑脊液标本用于病毒分离，以及162对血清用于病毒抗体检测。腮腺炎病毒感染仅在5%的病例中是该病的病因。证实了肠道病毒的主要病因作用。最常与疾病相关的毒株是埃可病毒6型和14型、柯萨奇病毒A9型和不可分型毒株。分离出的其他毒株是埃可病毒2型、9型、11型和20型。