Homan H, Ohtubo Y, Ito H, Azuma K, Yasumoto Y, Ohtuka H, Uomizu K, Yamashita W, Uemura S, Ohsaki K
Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University, Japan.
Jpn J Med. 1990 Mar-Apr;29(2):212-5. doi: 10.2169/internalmedicine1962.29.212.
IgD multiple myeloma is a unique type of multiple myeloma which is characterized by increased serum IgD and IgD type M-component in immunoelectrophoresis. It frequently shows renal involvement but it is a rare form of myeloma. The distinctive features of IgD myeloma are the dominance in males, high frequency in younger persons, and the uncertain appearance of M-component in serum electrophoresis. We experienced 3 cases of IgD multiple myeloma with renal failure which required hemodialysis before IgD myeloma was diagnosed. It is important to consider IgD myeloma when treating the patients with renal involvement of unknown origin.
IgD型多发性骨髓瘤是一种独特类型的多发性骨髓瘤，其特征为血清IgD升高以及免疫电泳中出现IgD型M蛋白成分。它常表现为肾脏受累，但却是骨髓瘤的一种罕见形式。IgD型骨髓瘤的显著特点是男性占主导、在年轻人中发病率较高，以及血清电泳中M蛋白成分的表现不明确。我们诊治了3例IgD型多发性骨髓瘤合并肾衰竭的患者，在诊断IgD型骨髓瘤之前均需要进行血液透析。在治疗不明原因肾脏受累的患者时，考虑IgD型骨髓瘤很重要。
