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尿路上皮细胞癌的骨骼肌转移

Skeletal muscle metastases from urothelial cell carcinoma.

作者信息

Doo Seung Whan, Kim Woong Bin, Kim Bong Ki, Yang Won Jae, Yoon Jong Hyun, Song Yun Seob, Choi In Ho

机构信息

Department of Urology, Soonchunhyang University College of Medicine, Seoul, Korea.

出版信息

Korean J Urol. 2012 Jan;53(1):63-6. doi: 10.4111/kju.2012.53.1.63. Epub 2012 Jan 25.

Abstract

Hematogenous metastasis to skeletal muscle from urothelial carcinoma is extremely rare and metastatic disease to skeletal muscle tends to be found in people with advanced-stage neoplasm. We report in this paper a case of left sartorius muscle metastasis from urothelial cell carcinoma. A left nephroureterectomy with bladder cuff excision was performed and revealed a high-grade papillary transitional cell carcinoma (TCC) of the pelvis. And 6 month later, recurrent bladder cancer was found regular cystoscopy and then treated with transurethral resection of the bladder. After 6 times resection of bladder, an invasion into the bladder muscle layer was found. We recommended additional radical cystectomy to prevent the disease from advancing. However, the patient refused additional surgery. 6 month later, the patient complained of left thigh pain, so ultrasonography-guided biopsy of the nodular mass lesion in the left sartorius muscle was performed. The pathological analysis of the biopsy specimen revealed poorly differentiated metastatic urothelial carcinoma.

摘要

尿路上皮癌经血行转移至骨骼肌极为罕见,且骨骼肌转移性疾病多见于晚期肿瘤患者。本文报告一例尿路上皮细胞癌转移至左缝匠肌的病例。患者接受了左肾输尿管切除术及膀胱袖口切除术,术中发现盆腔高级别乳头状移行细胞癌(TCC)。6个月后,定期膀胱镜检查发现复发性膀胱癌,随后接受经尿道膀胱切除术治疗。在进行6次膀胱切除术后,发现肿瘤侵犯膀胱肌层。我们建议进行额外的根治性膀胱切除术以防止疾病进展。然而,患者拒绝接受额外手术。6个月后,患者主诉左大腿疼痛,因此对左缝匠肌的结节状肿块病变进行了超声引导下活检。活检标本的病理分析显示为低分化转移性尿路上皮癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3985/3272560/3caa70d8cd78/kju-53-63-g001.jpg

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