Klune John R, Zuckerbraun Brian, Tsung Allan
Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Int Semin Surg Oncol. 2010 Feb 28;7(1):1. doi: 10.1186/1477-7800-7-1.
Skeletal muscle metastases from tumors are a rare occurrence and can present difficult management decisions. We report here on a patient that had been previously treated for squamous cell laryngeal cancer with surgical resection and adjuvant systemic chemotherapy that presented with a metastasis to the rectus abdominis muscle without evidence of recurrent disease at the primary site. After a metastatic workup with PET/CT scan suggested this to be an isolated lesion, surgical excision with negative margins was performed based upon limited treatment options secondary to the location of the tumor and his favorable prognosis suggested by his pathological staging at the time of the initial resection. Here we discuss the incidence of distant metastases from laryngeal cancer and appropriate screening methods. Additionally, skeletal muscle metastases and treatment considerations are discussed.
肿瘤的骨骼肌转移很少见，可能带来棘手的治疗决策。我们在此报告一名患者，其先前接受过手术切除及辅助全身化疗以治疗喉鳞状细胞癌，现出现腹直肌转移，而原发部位无复发疾病迹象。经PET/CT扫描进行转移灶检查提示这是一个孤立性病变，鉴于肿瘤位置导致治疗选择有限，且根据初次切除时的病理分期提示其预后良好，遂进行了切缘阴性的手术切除。在此我们讨论喉癌远处转移的发生率及合适的筛查方法。此外，还讨论了骨骼肌转移及治疗注意事项。
