School of Public Health, Physiotherapy and Population Science, University College Dublin, Ireland.
Clin Rehabil. 2012 Oct;26(10):867-81. doi: 10.1177/0269215511431902. Epub 2012 Feb 9.
To assess the effectiveness of surface neuromuscular electrical stimulation in the treatment of knee osteoarthritis.
Systematic review and meta-analysis of randomized controlled and controlled clinical trials
Studies were identified from databases (MEDLINE, EMBASE, CINAHL, Sports Discus, PEDro and the Cochrane Library) searched to January 2011 using a battery of keywords. Two reviewers selected studies meeting inclusion criteria. The methodological quality of the included studies was assessed using the Thomas Test and the strength of the evidence was then graded using the Agency for Health Care Policy and Research guidelines. Data were pooled and meta-analyses were performed.
Nine randomized controlled trials and one controlled clinical trial, studying a total of 409 participants (n = 395 for randomized controlled trials, and n = 14 for controlled trial) with a diagnosis of osteoarthritis were included. Inconsistent evidence (level D) was found that neuromuscular electrical stimulation has a significant impact on measures of pain, function and quadriceps femoris muscle strength in knee osteoarthritis.
The role of neuromuscular electrical stimulation in the treatment of knee osteoarthritis is ambiguous. Therefore, future work is needed in this field to clearly establish the role of neuromuscular electrical stimulation in this population.
评估表面神经肌肉电刺激治疗膝骨关节炎的效果。
对随机对照试验和对照临床试验进行系统评价和荟萃分析。
检索数据库（MEDLINE、EMBASE、CINAHL、Sports Discus、PEDro 和 Cochrane 图书馆），使用一套关键词搜索至 2011 年 1 月，两位评审员选择符合纳入标准的研究。采用 Thomas 测试评估纳入研究的方法学质量，然后根据卫生保健政策和研究机构的指南对证据强度进行分级。对数据进行汇总并进行荟萃分析。
共纳入 9 项随机对照试验和 1 项对照临床试验，研究对象共 409 人（n=395 例随机对照试验，n=14 例对照试验），诊断为骨关节炎。结果提示证据不一致（D 级），神经肌肉电刺激对膝骨关节炎的疼痛、功能和股四头肌力量的测量指标有显著影响。
神经肌肉电刺激在膝骨关节炎治疗中的作用尚不清楚。因此，该领域需要进一步研究，以明确神经肌肉电刺激在该人群中的作用。
