Totskiĭ V N, Filippova L B
Ukr Biokhim Zh (1978). 1979 May-Jun;51(3):241-5.
Nicotinic acid added to the incubation medium stimulates ATPase activity in erythrocytes and their membranes. Simultaneously the ouabain-sensitive ATPase activity is activated. The mentioned effect is not observed when lipoic acid is added to the medium. Accumulation of [14C]nicotinate and [35S]lipoate in biostructures occurs more intensely under conditions optimal for the Mg2+, Na+, K+-ATPase activity. In experiments with "traces" of erythrocytes it is shown that the gradient of Na+ and K+ favours to the transport of [35S] lipoate.
向孵育培养基中添加烟酸可刺激红细胞及其膜中的ATP酶活性。同时，哇巴因敏感的ATP酶活性被激活。当向培养基中添加硫辛酸时，未观察到上述效果。在对Mg2+、Na+、K+-ATP酶活性最适宜的条件下，生物结构中[14C]烟酸酯和[35S]硫辛酸酯的积累更为强烈。在使用微量红细胞进行的实验中表明，Na+和K+的梯度有利于[35S]硫辛酸酯的转运。
