Rambam Health Care Campus, Haifa, Israel; School of Medicine, The Technion, Israel Institute of Technology, Haifa, Israel.
J Am Soc Echocardiogr. 2012 May;25(5):543-52. doi: 10.1016/j.echo.2012.01.005. Epub 2012 Feb 10.
Echocardiographic imaging assessment of left ventricular mechanics is a new technology that is offered by various vendors. Different software algorithms have at times yielded conflicting results. The aim of this study was to determine normal myocardial mechanical parameters in a healthy population using Velocity Vector Imaging.
One hundred twenty subjects were selected for this study, including healthy subjects referred for echocardiography to evaluate minor symptoms or murmurs, who had normal echocardiographic findings and healthy volunteers. Study subjects were recruited in Haifa, Israel and Toronto, Canada. Echocardiography was performed using commercially available systems to analyze archived studies. Endocardial and epicardial longitudinal and circumferential strain and strain rate were calculated as well as rotational mechanical parameters. Age and gender differences were evaluated.
Average endocardial longitudinal, circumferential, and radial strains and twist were -19.6 ± 2.0%, -27.6 ± 3.9%, +30.1 ± 7.5%, and 9.6 ± 3.9°, respectively. Epicardial circumferential strain and twist were -11.3 ± 2.2% and 4.0 ± 1.9°, respectively. Shortening increased from base to apex longitudinally (10%) and circumferentially (33%). Thickening at the apex was 16% lower than at the base. Men and older subjects had increased endocardial circumferential strain and apical rotation.
Mechanical parameters differ with location (endocardial vs epicardial, basal vs apical strain gradients), age, and gender. Care should be taken when comparing regional strain measurements between systems, and gender and age should be matched between and within two-dimensional strain systems.
超声心动图左心室力学成像评估是一种新技术，由不同供应商提供。不同的软件算法有时会产生相互矛盾的结果。本研究旨在使用速度向量成像技术确定健康人群的正常心肌力学参数。
本研究选择了 120 名受试者，包括因轻微症状或杂音而接受超声心动图检查的健康受试者，这些受试者均有正常的超声心动图发现和健康志愿者。研究对象在以色列海法和加拿大多伦多招募。使用商业上可用的系统进行超声心动图检查，以分析存档的研究。计算心内膜和心外膜的纵向和周向应变和应变率以及旋转力学参数。评估年龄和性别差异。
平均心内膜纵向、周向和径向应变和扭转分别为-19.6±2.0%、-27.6±3.9%、+30.1±7.5%和 9.6±3.9°。心外膜周向应变和扭转分别为-11.3±2.2%和 4.0±1.9°。纵向（10%）和周向（33%）从基底到心尖缩短增加。心尖处的增厚比基底处低 16%。男性和年龄较大的受试者心内膜周向应变和心尖旋转增加。
力学参数因位置（心内膜与心外膜、基底与心尖应变梯度）、年龄和性别而异。在比较系统之间的局部应变测量值时应小心谨慎，并且在二维应变系统中应在组间和组内匹配性别和年龄。
