Department of Ultrasound, Xinqiao Hospital, Third Military Medical University, Chongqing, China.
Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, 200 First St SW, Rochester, MN, 55905, USA.
BMC Cardiovasc Disord. 2020 Jun 5;20(1):274. doi: 10.1186/s12872-020-01559-1.
Ventricular strain measurements vary depending on cardiac chamber (left ventricle [LV] or right ventricle [RV]), type of strain (longitudinal, circumferential, or radial), ventricular level (basal, mid, or apical), myocardial layer (endocardial or epicardial), and software used for analysis, among other demographic factors such as age and gender. Here, we present an analysis of ventricular strain taking all of these variables into account in a cohort of patients with no structural heart disease using a vendor-independent speckle-tracking software.
LV and RV full-thickness strain parameters were retrospectively measured in 102 patients (mean age 39 ± 15 years; 62% female). Within this cohort, we performed further layer-specific strain analysis in 20 subjects. Data were analyzed for global and segmental systolic strain, systolic strain rate, early diastolic strain rate, and their respective time-to-peak values.
Mean LV global longitudinal, circumferential, and radial strain values for the entire cohort were - 18.4 ± 2.0%, - 22.1 ± 4.1%, and 43.9 ± 12.1% respectively, while mean RV global and free wall longitudinal strain values were - 24.2 ± 3.9% and - 26.1 ± 5.2% respectively. Women on average demonstrated higher longitudinal and circumferential strain and strain rate than men, and longer corresponding time-to-peak values. Longitudinal strain measurements were highest at the apex compared with the mid ventricle and base, and in the endocardium compared with the epicardium. Longitudinal strain was the most reproducible measure, followed closely by circumferential strain, while radial strain showed suboptimal reproducibility.
We present an analysis of ventricular strain in patients with no structural heart disease using a vendor-independent speckle-tracking software.
心室应变测量值因心脏腔室（左心室[LV]或右心室[RV]）、应变类型（纵向、环向或径向）、心室水平（基底、中部或心尖）、心肌层（心内膜或心外膜）以及用于分析的软件等因素而有所不同，此外还包括年龄和性别等人口统计学因素。在这里，我们使用一种与供应商无关的斑点追踪软件，在一组无结构性心脏病患者中分析了考虑所有这些变量的心室应变。
回顾性测量了 102 例患者（平均年龄 39±15 岁；62%为女性）的 LV 和 RV 全层应变参数。在该队列中，我们对 20 例患者进行了进一步的层特异性应变分析。分析了整体和节段性收缩期应变、收缩期应变率、早期舒张期应变率及其各自的达峰时间。
整个队列的 LV 整体纵向、环向和径向应变值分别为-18.4±2.0%、-22.1±4.1%和 43.9±12.1%，而 RV 整体和游离壁纵向应变值分别为-24.2±3.9%和-26.1±5.2%。女性的纵向和环向应变及应变率平均高于男性，相应的达峰时间也较长。与中部心室和基底相比，心尖处的纵向应变测量值最高，与心外膜相比，心内膜处的纵向应变测量值最高。与环向应变相比，纵向应变的重复性最好，其次是环向应变，而径向应变的重复性较差。
我们使用一种与供应商无关的斑点追踪软件，分析了无结构性心脏病患者的心室应变。
