Clinic for Preventive Dentistry, Periodontology and Cariology, University of Zürich, Zürich, Switzerland.
J Dent. 2012 May;40(5):416-22. doi: 10.1016/j.jdent.2012.02.003. Epub 2012 Feb 9.
To test sealants to prevent erosive tooth wear caused by extrinsic and intrinsic acids under long-term exposition.
144 bovine enamel samples were randomly allocated to twelve groups (1-12). Samples of groups 1, 5 and 9 remained unsealed (positive controls), 2, 6 and 10 were sealed with Silicon Seal Nano Mix and 3, 7 and 11 with Seal&Protect. Groups 4, 8 and 12 were sealed with flowable composite (negative controls). Groups 1-4 were immersed in artificial saliva, 5-8 in hydrochloric acid and groups 9-12 in citric acid for 28 days, respectively. After 1, 2, 4, 7, 11, 14, 21 and 28 days, solutions were renewed and enamel wear was quantified by assignation of (32)P in the solutions.
In all immersion solutions, lowest mineral loss was observed for the negative controls whilst highest loss was observed for unsealed positive controls. In artificial saliva and citric acid, the loss from samples sealed with Seal&Protect was not significantly different compared with negative controls whilst loss in groups sealed with Silicon Seal Nano Mix was significantly higher. In hydrochloric acid, loss from samples sealed with Seal&Protect was not different compared with that of negative controls up to 4 days. Except day 1, the mineral loss in the Seal&Protect group was significantly lower compared with that of the Silicon Seal Nano Mix group.
The tested resin based surface sealant is able to significantly reduce the erosive demineralisation of enamel caused by hydrochloric and citric acid even under long-term exposition.
测试密封剂以防止长期暴露于外源性和内源性酸引起的侵蚀性牙齿磨损。
将 144 个牛牙釉质样本随机分配到 12 个组(1-12)。第 1、5 和 9 组的样本未密封(阳性对照),第 2、6 和 10 组用 Silicon Seal Nano Mix 密封,第 3、7 和 11 组用 Seal&Protect 密封。第 4、8 和 12 组用流动复合树脂密封(阴性对照)。第 1-4 组在人工唾液中浸泡,第 5-8 组在盐酸中浸泡,第 9-12 组在柠檬酸中浸泡 28 天。第 1、2、4、7、11、14、21 和 28 天后,更换溶液并通过在溶液中分配(32)P 来定量牙釉质磨损。
在所有浸泡溶液中,阴性对照的矿物质损失最低,而未密封的阳性对照的损失最高。在人工唾液和柠檬酸中,与阴性对照相比,用 Seal&Protect 密封的样本的损失没有显著差异,而用 Silicon Seal Nano Mix 密封的样本的损失则显著更高。在盐酸中,用 Seal&Protect 密封的样本的损失在 4 天内与阴性对照无差异。除第 1 天外,Seal&Protect 组的矿物质损失明显低于 Silicon Seal Nano Mix 组。
测试的基于树脂的表面密封剂能够显著减少盐酸和柠檬酸引起的牙釉质侵蚀性脱矿,即使在长期暴露下也是如此。