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围绝经期和绝经后妇女的焦虑、抑郁和失眠之间的关联。

Associations between anxiety, depression and insomnia in peri- and post-menopausal women.

机构信息

Department of Obstetrics and Gynecology, Tokyo Medical and Dental University, Tokyo, Japan.

出版信息

Maturitas. 2012 May;72(1):61-5. doi: 10.1016/j.maturitas.2012.01.014. Epub 2012 Feb 11.

DOI:10.1016/j.maturitas.2012.01.014
PMID:22326659
Abstract

OBJECTIVES

To determine the correlation between somatic and psychological symptoms and insomnia and the contribution of depression and anxiety to insomnia in a sample of peri- and post-menopausal women in a clinical setting.

STUDY DESIGN

The responses of 237 peri- and post-menopausal women enrolled in the Systematic Health and Nutrition Education Program (SHNEP) at the Menopause Clinic of the Tokyo Medical and Dental University Hospital between November 2007 and December 2010 to the Menopausal Health-Related Quality of Life (MHR-QOL) and Hospital Anxiety and Depression Scale (HADS) questionnaires were subjected to Spearman's rank correlation and logistic regression analyses.

RESULTS

The analysis revealed that (1) insomnia is highly prevalent, (2) the symptoms of difficulty in initiating sleep (DIS) and experiencing non-restorative sleep (NRS) are more strongly correlated with psychological than somatic symptoms, and (3) DIS is strongly associated with anxiety while NRS is strongly associated with depression in the population studied.

CONCLUSIONS

Insomnia is highly prevalent among peri- and post-menopausal female patients in a clinical setting and more closely associated with psychological than somatic symptoms. DIS is strongly correlated with anxiety while NRS is strongly correlated with depression.

摘要

目的

在临床环境中,确定围绝经期和绝经后妇女的躯体和心理症状与失眠之间的相关性,以及抑郁和焦虑对失眠的影响。

研究设计

2007 年 11 月至 2010 年 12 月,东京医科齿科大学医院绝经诊所参加系统性健康与营养教育计划(SHNEP)的 237 名围绝经期和绝经后妇女对绝经相关生活质量(MHR-QOL)和医院焦虑抑郁量表(HADS)问卷的回答进行了 Spearman 等级相关和逻辑回归分析。

结果

分析显示:(1)失眠的患病率很高;(2)入睡困难(DIS)和睡眠质量差(NRS)的症状与心理症状的相关性强于躯体症状;(3)在研究人群中,DIS 与焦虑密切相关,而 NRS 与抑郁密切相关。

结论

在临床环境中,围绝经期和绝经后女性患者失眠的患病率很高,与心理症状的相关性强于躯体症状。DIS 与焦虑密切相关,而 NRS 与抑郁密切相关。

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