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本文引用的文献

1
Thyroid cancer risk 40+ years after irradiation for an enlarged thymus: an update of the Hempelmann cohort.40 多年后因胸腺肿大接受放射治疗的甲状腺癌风险:Hempelmann 队列的更新。
Radiat Res. 2010 Dec;174(6):753-62. doi: 10.1667/RR2181.1. Epub 2010 Oct 26.
2
Risk of second primary thyroid cancer after radiotherapy for a childhood cancer in a large cohort study: an update from the childhood cancer survivor study.在大型队列研究中,儿童癌症放疗后第二原发甲状腺癌的风险:来自儿童癌症幸存者研究的更新。
Radiat Res. 2010 Dec;174(6):741-52. doi: 10.1667/RR2240.1. Epub 2010 Oct 6.
3
Radiation hormesis: historical perspective and implications for low-dose cancer risk assessment.辐射兴奋效应:历史透视及其对低剂量癌症风险评估的意义。
Dose Response. 2010 Jan 18;8(2):172-91. doi: 10.2203/dose-response.09-037.Vaiserman.
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Observations on the Chernobyl Disaster and LNT.切尔诺贝利灾难与线性无阈理论观察
Dose Response. 2010 Jan 28;8(2):148-71. doi: 10.2203/dose-response.09-029.Jaworowski.
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Cervical spine clearance in pediatric trauma: a review of current literature.小儿创伤中的颈椎评估:当前文献综述
J Trauma. 2009 Oct;67(4):687-91. doi: 10.1097/TA.0b013e3181b5ecae.
6
Practice management guidelines for identification of cervical spine injuries following trauma: update from the eastern association for the surgery of trauma practice management guidelines committee.创伤后颈椎损伤识别的实践管理指南:来自东部创伤外科学会实践管理指南委员会的更新
J Trauma. 2009 Sep;67(3):651-9. doi: 10.1097/TA.0b013e3181ae583b.
7
Radiation exposure from musculoskeletal computerized tomographic scans.肌肉骨骼计算机断层扫描的辐射暴露
J Bone Joint Surg Am. 2009 Aug;91(8):1882-9. doi: 10.2106/JBJS.H.01199.
8
Increasing incidence of differentiated thyroid cancer in the United States, 1988-2005.1988 - 2005年美国分化型甲状腺癌发病率上升
Cancer. 2009 Aug 15;115(16):3801-7. doi: 10.1002/cncr.24416.
9
Rising thyroid cancer incidence in the United States by demographic and tumor characteristics, 1980-2005.1980 - 2005年美国按人口统计学和肿瘤特征划分的甲状腺癌发病率上升情况
Cancer Epidemiol Biomarkers Prev. 2009 Mar;18(3):784-91. doi: 10.1158/1055-9965.EPI-08-0960. Epub 2009 Feb 24.
10
Traumatic cervical spine injuries: characteristics of missed injuries.创伤性颈椎损伤:漏诊损伤的特征
J Pediatr Surg. 2009 Jan;44(1):151-5; discussion 155. doi: 10.1016/j.jpedsurg.2008.10.024.

儿童创伤患者颈椎多排 CT 检查甲状腺癌诱导的理论增加。

Theoretical increase of thyroid cancer induction from cervical spine multidetector computed tomography in pediatric trauma patients.

机构信息

Department of Orthopedic Surgery, University of Wisconsin-Madison, 1685 Highland Avenue, Madison, WI 53705, USA.

出版信息

J Trauma Acute Care Surg. 2012 Feb;72(2):403-9. doi: 10.1097/TA.0b013e31823a4bd7.

DOI:10.1097/TA.0b013e31823a4bd7
PMID:22327982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4495661/
Abstract

BACKGROUND

The trend of increasing cervical spine multidirectional computed tomography (MDCT) imaging of pediatric trauma patients is characteristic of the overall dramatic increase in computed tomography utilization in the United States. The purpose of this study is to compare the amount of radiation a pediatric trauma patient absorbs to the thyroid from plain radiographs and MDCT of the cervical spine and to express risk by calculation of theoretical thyroid cancer induction.

METHODS

A retrospective evaluation of pediatric trauma patients admitted from October 1, 2004, to October 31, 2009, was performed at an academic, Level I trauma center. Inclusion criteria were Level I/II trauma patients, cervical spine imaging performed at our institution, and age <18 years. Absorbed thyroid radiation was calculated for patients receiving plain radiographs or MDCT. Thyroid cancer risk was calculated using the 2006 Biological Effects on Ionizing Radiation VII report.

RESULTS

Six hundred seventeen patients met inclusion criteria: 224 received cervical spine radiographs and 393 received cervical spine MDCT. The mean thyroid radiation absorbed from radiographs was 0.90 mGy for males and 0.96 mGy for females compared with 63.6 mGy (males) and 64.2 mGy (females) receiving MDCT (p < 0.001). The median excess relative risk of thyroid cancer induction from one cervical spine MDCT in males was 13.0% and females was 25.0%, compared with 0.24% (males) and 0.51% (females) for radiographs (p < 0.001).

CONCLUSIONS

The significant difference in radiation that MDCT delivers to the pediatric trauma patient when compared with plain radiographs should temper routine use of computed tomography in pediatric cervical spine clearance algorithms.

摘要

背景

儿科创伤患者颈椎多排 CT(MDCT)成像趋势是美国 CT 使用率整体大幅增加的特征。本研究的目的是比较儿科创伤患者接受颈椎平片和 MDCT 检查时甲状腺吸收的辐射量,并通过计算理论甲状腺癌诱导来表示风险。

方法

对 2004 年 10 月 1 日至 2009 年 10 月 31 日在学术性一级创伤中心收治的儿科创伤患者进行回顾性评估。纳入标准为一级/二级创伤患者、在我院进行颈椎影像学检查、年龄<18 岁。对接受平片或 MDCT 检查的患者计算甲状腺吸收的辐射量。使用 2006 年《电离辐射生物效应报告》VII 报告计算甲状腺癌风险。

结果

617 例患者符合纳入标准:224 例接受颈椎平片检查,393 例接受颈椎 MDCT 检查。男性和女性从平片吸收的甲状腺辐射平均值分别为 0.90 mGy 和 0.96 mGy,而接受 MDCT 的男性和女性分别为 63.6 mGy 和 64.2 mGy(p<0.001)。从一次 MDCT 颈椎检查中男性甲状腺癌诱导的中位超额相对风险为 13.0%,女性为 25.0%,而平片检查的男性为 0.24%,女性为 0.51%(p<0.001)。

结论

与平片相比,MDCT 对儿科创伤患者的辐射量差异显著,应调整儿科颈椎清除算法中 CT 的常规使用。