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肝移植受者的焦虑与抑郁及其影响因素

[Anxiety and depression for liver transplant recipients and their impact factors].

作者信息

Wang Gen-shu, Zhang Qi, Li Hua, Jiang Nan, Fu Bin-sheng, Zhang Jian, Jin Hai, Yang Jian-xu, Yang Yang, Chen Gui-Hua

机构信息

Institute of Organ Transplantation, Sun Yat-Sen University, Guangzhou, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2011 Nov 22;91(43):3077-9.

Abstract

OBJECTIVE

To investigate the status of anxiety and depression for liver transplant (LT) recipients and explore their impact factors.

METHODS

During the period of January 2005 to December 2008, the symptoms of anxiety and depression for 53 post-LT recipients (LT group) and 48 patients with benign end-stage liver disease (BELD group) were assessed by the self-rating anxiety scale (SAS) and the self-rating depression scale (SDS). And they were compared with that of domestic norm (Norm group). The impact factors of anxiety and depression for LT recipients were analyzed by stepwise logistic regression.

RESULTS

The anxiety scores of LT, BELD and Norm groups were (42 ± 9), (47 ± 11) and (30 ± 10) and the depression scores of three groups (48 ± 11), (52 ± 11) and (33 ± 9) respectively. The anxiety score was different significantly among three groups (P < 0.01). It was higher in the LT and BELD groups than that in the Norm Group (P < 0.01) while it was lower in the LT group than that in the BELD group (P < 0.05). The depression scores were different significantly among three groups (P < 0.01). It was higher in the LT and BELD groups than that in the Norm Group. And it was lower in the LT group than that in the BELD group (P < 0.05). The impact factor of anxiety for LT recipients was patient age and that of depression per capita monthly family income.

CONCLUSION

The level of anxiety and depression of post-LT recipients is higher than that of domestic norm. The main impact factor for post-LT anxiety is patient age and that of depression per capita monthly family income.

摘要

目的

调查肝移植受者焦虑和抑郁状况并探讨其影响因素。

方法

2005年1月至2008年12月期间,采用自评焦虑量表(SAS)和自评抑郁量表(SDS)对53例肝移植术后受者(肝移植组)和48例良性终末期肝病患者(BELD组)的焦虑和抑郁症状进行评估,并与国内常模(常模组)进行比较。采用逐步逻辑回归分析肝移植受者焦虑和抑郁的影响因素。

结果

肝移植组、BELD组和常模组的焦虑得分分别为(42±9)、(47±11)和(30±10),三组的抑郁得分分别为(48±11)、(52±11)和(33±9)。三组间焦虑得分差异有统计学意义(P<0.01)。肝移植组和BELD组高于常模组(P<0.01),肝移植组低于BELD组(P<0.05)。三组间抑郁得分差异有统计学意义(P<0.01)。肝移植组和BELD组高于常模组,肝移植组低于BELD组(P<0.05)。肝移植受者焦虑的影响因素为患者年龄,抑郁的影响因素为人均月家庭收入。

结论

肝移植术后受者焦虑和抑郁水平高于国内常模。肝移植术后焦虑的主要影响因素为患者年龄,抑郁的主要影响因素为人均月家庭收入。

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