Santra Gouranga, Sinha Pradip Kumar, De Dibyendu
Dept. of Medicine, Medical College, 88, College Street, Kolkata-700073.
J Assoc Physicians India. 2011 Sep;59:595-7.
Occurrence of glomerular diseases in psoriasis is rare, although the number of reports is increasing in recent years. Different types of glomerular involvement have been reported but mesangioproliferative glomerulonephritis with IgA deposits, AA amyloidosis and membranous nephropathy are relatively common in association with psoriasis. The term 'psoriatic nephropathy' has been introduced recently. We contribute a case to the ongoing discussin regarding psoriatic nephropathy. Our patient had mesangio-proliferative glomerulonephritis (with IgG and C3 deposition) in association with annular psoriasis (rare variety of chronic plaque psoriasis). Presence of messangio-proliferative glomerulonephritis with IgG deposition is rare in association with psoriasis. The patient responded well to weekly methotrexate (15 mg) injection. Methotrexate has not been tried previously in psoriatic nephropathy or reported to be effective in it.
银屑病患者中肾小球疾病的发生较为罕见，尽管近年来相关报道的数量在增加。已有不同类型肾小球受累的报道，但伴有IgA沉积的系膜增生性肾小球肾炎、AA淀粉样变性和膜性肾病在银屑病患者中相对常见。“银屑病肾病”这一术语最近才被提出。我们为正在进行的关于银屑病肾病的讨论提供了一个病例。我们的患者患有系膜增生性肾小球肾炎（伴有IgG和C3沉积），同时伴有环状银屑病（慢性斑块状银屑病的罕见类型）。伴有IgG沉积的系膜增生性肾小球肾炎在银屑病患者中较为罕见。该患者对每周注射甲氨蝶呤（15毫克）反应良好。此前尚未在银屑病肾病中尝试使用甲氨蝶呤，也没有关于其在该病中有效的报道。
