Institut National de la Santé et de la Recherche Médicale (INSERM), U895, Nice F-06204, Cedex 3, France.
J Clin Virol. 2012 May;54(1):76-8. doi: 10.1016/j.jcv.2012.01.016. Epub 2012 Feb 14.
In European countries, epidemiology of hepatitis E virus (HEV) infection is not well known. Although, seroprevalence of HEV Immunoglobulin G reached a few percent in European women, no acute hepatitis E during pregnancy has been described so far. Here, we report a case of an autochthonous HEV genotype 3 infection in a 41-years-old pregnant woman living in a non-endemic country. The acute hepatitis had a spontaneous good outcome for the mother and the child. In non-endemic areas where Hepatitis E infections are emerging, unexplained cytolysis, whatever its level, in a pregnant woman could be investigated for HEV, using biological molecular and serology tools.
在欧洲国家,戊型肝炎病毒(HEV)感染的流行病学情况并不为人所知。虽然,在欧洲妇女中,HEV 免疫球蛋白 G 的血清阳性率达到了几个百分点,但迄今为止尚未描述过妊娠期急性戊型肝炎。在这里,我们报告了一例发生在非流行地区的 41 岁孕妇的本土 HEV 基因型 3 感染。急性肝炎对母亲和孩子都有自发的良好结局。在戊型肝炎感染正在出现的非流行地区,对于任何不明原因的孕妇细胞溶解症,无论其程度如何,都可以使用生物分子和血清学工具进行 HEV 检测。