Department of Surgery, University of California, Irvine, Medical Center, Orange, California 92868, USA.
Surg Obes Relat Dis. 2013 Mar-Apr;9(2):239-46. doi: 10.1016/j.soard.2011.12.010. Epub 2011 Dec 22.
An obesity surgery mortality risk score derived from a single clinical series can be used to stratify the mortality risk of patients undergoing gastric bypass. However, such a scoring system does not take into account 2 important factors in contemporary bariatric surgery--increased use of the laparoscopic approach and laparoscopic adjustable gastric banding. The present study analyzed the preoperative factors that might predict in-hospital mortality after bariatric surgery using data from academic medical centers and proposes a classification system for predicting mortality.
Using the "International Classification of Diseases, 9th revision," diagnosis and procedural codes, the data for all patients who underwent bariatric surgery for the treatment of morbid obesity from 2002 to 2009 were obtained from the University HealthSystem Consortium database. The limitations of this database included the lack of the body mass index and the underestimation of some co-morbidities, such as sleep apnea. Multiple regression analyses were performed to determine the factors predictive of greater in-hospital mortality. The factors examined included race, gender, age, co-morbidities, surgical technique (laparoscopic versus open), bariatric operation (gastric bypass versus nongastric bypass), and payer type. A scoring system was devised by assigning 1 point for each major factor (those with an adjusted odds ratio [AOR] of ≥2.0) and .5 point for each minor factor (those with an AOR <2.0). Using contemporary data from 2007 to 2009, the in-hospital mortality was analyzed according to the classification: class I, 0-0.5 point; class II, 1.0-1.5 points; class III, 2.0-3.0 points; and class IV, ≥3.5 points.
During the 8-year period, 105,287 patients underwent bariatric surgery. The operations included laparoscopic gastric bypass (45%), open gastric bypass (41%), and laparoscopic gastric banding or gastroplasty (14%). The overall in-hospital mortality rate was .17%. The number of deaths per 1000 bariatric operations decreased from 4.0 in 2002 to .6 in 2009. Using regression analyses, the factors predictive of greater in-hospital mortality were male gender (AOR 3.2), gastric bypass procedure (AOR 5.8), open surgical technique (AOR 4.8), Medicare payer (AOR 3.0), diabetes (AOR 1.6), and age >60 years (AOR 1.9). The mortality rate was .10% for class I patients, .15% for class II, .33% for class III, and .70% for class IV (P < .05 among all classes).
Within the context of academic centers, the mortality after bariatric surgery has decreased substantially since 2002, with an increase in the use of the laparoscopic technique and laparoscopic gastric banding. A bariatric mortality risk classification system was developed to stratify mortality, given the limits of this database, which does not include the body mass index and underestimates the incidence of sleep apnea. It might be useful to aid surgeons in surgical decision-making, to inform patients of their risks, and for quality improvement reporting purposes.
从单一临床系列中得出的肥胖手术死亡率风险评分可用于对接受胃旁路手术的患者进行死亡率风险分层。然而,这种评分系统并未考虑到当代减重手术中的 2 个重要因素——腹腔镜方法和腹腔镜可调胃束带的使用增加。本研究使用来自学术医疗中心的数据,分析了可能预测减重手术后住院期间死亡率的术前因素,并提出了一种预测死亡率的分类系统。
使用“国际疾病分类,第 9 版”诊断和程序代码,从 2002 年至 2009 年,从大学健康联盟数据库中获取了所有因病态肥胖而行减重手术的患者的数据。该数据库的局限性包括缺乏体重指数和一些合并症(如睡眠呼吸暂停)的低估。进行多变量回归分析以确定与更高住院死亡率相关的因素。检查的因素包括种族、性别、年龄、合并症、手术技术(腹腔镜与开放)、减重手术(胃旁路术与非胃旁路术)和付款人类型。通过为每个主要因素(调整后比值比 [AOR]≥2.0)分配 1 分,为每个次要因素(AOR<2.0)分配.5 分,设计了一个评分系统。使用 2007 年至 2009 年的当代数据,根据分类分析住院期间死亡率:I 级,0-0.5 分;II 级,1.0-1.5 分;III 级,2.0-3.0 分;IV 级,≥3.5 分。
在 8 年期间,有 105287 名患者接受了减重手术。手术包括腹腔镜胃旁路术(45%)、开放胃旁路术(41%)和腹腔镜胃束带或胃成形术(14%)。总的住院死亡率为.17%。每 1000 例减重手术的死亡人数从 2002 年的 4.0 例减少到 2009 年的 0.6 例。使用回归分析,与更高住院死亡率相关的因素是男性(AOR 3.2)、胃旁路手术(AOR 5.8)、开放手术技术(AOR 4.8)、医疗保险支付人(AOR 3.0)、糖尿病(AOR 1.6)和年龄>60 岁(AOR 1.9)。I 级患者的死亡率为.10%,II 级为.15%,III 级为.33%,IV 级为.70%(所有级别之间的 P<.05)。
在学术中心中,自 2002 年以来,减重手术后的死亡率大幅下降,腹腔镜技术和腹腔镜可调胃束带的使用有所增加。鉴于该数据库的局限性,包括缺乏体重指数和低估睡眠呼吸暂停的发生率,制定了减重手术死亡率风险分类系统来分层死亡率。它可能有助于辅助外科医生进行手术决策,告知患者其风险,并用于质量改进报告目的。