SUPA, School of Physics and Astronomy, University of Edinburgh, Mayfield Road, Edinburgh EH9 3JZ, UK.
J R Soc Interface. 2012 Jun 7;9(71):1398-408. doi: 10.1098/rsif.2011.0868. Epub 2012 Feb 15.
We present a computer simulation study, via lattice Boltzmann simulations, of a microscopic model for cytoplasmic streaming in algal cells such as those of Chara corallina. We modelled myosin motors tracking along actin lanes as spheres undergoing directed motion along fixed lines. The sphere dimension takes into account the fact that motors drag vesicles or other organelles, and, unlike previous work, we model the boundary close to which the motors move as walls with a finite slip layer. By using realistic parameter values for actin lane and myosin density, as well as for endoplasmic and vacuole viscosity and the slip layer close to the wall, we find that this simplified view, which does not rely on any coupling between motors, cytoplasm and vacuole other than that provided by viscous Stokes flow, is enough to account for the observed magnitude of streaming velocities in intracellular fluid in living plant cells.
我们通过晶格玻尔兹曼模拟展示了一个藻类细胞（如珊瑚藻）胞质流动的微观模型的计算机模拟研究。我们将肌球蛋白沿着肌动蛋白轨道追踪建模为沿着固定线进行定向运动的球体。球体的尺寸考虑到了这样一个事实，即马达拖动囊泡或其他细胞器，与之前的工作不同，我们将靠近马达运动的边界建模为具有有限滑移层的墙壁。通过使用实际的肌动蛋白轨道和肌球蛋白密度、内质网和液泡粘度以及靠近壁的滑移层的参数值，我们发现，这种简化的观点，除了粘性斯托克斯流提供的马达、细胞质和液泡之间的耦合之外，不需要依赖任何其他耦合，足以解释活植物细胞内细胞液中观察到的流动速度。
