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空气污染与加拿大温莎市哮喘急诊

Air pollution and emergency department visits for asthma in Windsor, Canada.

机构信息

Environmental Issues Division, Public Health Agency of Canada, Ottawa, ON.

出版信息

Can J Public Health. 2012 Jan-Feb;103(1):4-8. doi: 10.1007/BF03404060.

Abstract

OBJECTIVES

The city of Windsor is recognized to have poor air quality in comparison with other Canadian cities. However, relatively few studies have evaluated associations between day-to-day fluctuations in air pollution levels and respiratory health in Windsor. In this study, we examined associations between short-term changes in ambient air pollution and emergency department (ED) visits for asthma in Windsor.

METHODS

A time-stratified case-crossover design was applied to 3,728 ED visits for asthma that occurred in Windsor area hospitals between 2002 and 2009. Daily air pollution levels for the region were estimated using Environment Canada's network of fixed-site monitors. ED visits were identified through the National Ambulatory Care Reporting System (NACRS). Odds ratios and their corresponding 95% confidence intervals were estimated using conditional logistic regression, and were adjusted for the confounding influence of daily number of influenza ED visits and weather variables using natural spline functions.

RESULTS

Statistically significant associations were observed between ambient air pollution levels and ED visits for asthma in Windsor. Effects were particularly pronounced among children 2 to 14 years of age between April and September. Namely, increases in the interquartile range with 1-day lagged exposure to SO2, NO2 and CO levels were associated with increased risks of an asthma visit of 19%, 25% and 36%, respectively.

CONCLUSION

Exposure in Windsor to ambient air pollution increases the risk of ED visits for asthma, particularly among children.

摘要

目的

与其他加拿大城市相比,温莎市的空气质量较差已得到公认。然而,评估温莎市空气污染水平的日常波动与呼吸道健康之间的关联的研究相对较少。在这项研究中,我们研究了温莎市环境空气中短期变化与哮喘急诊就诊之间的关系。

方法

本研究采用时间分层病例交叉设计,分析了 2002 年至 2009 年期间温莎地区医院因哮喘而发生的 3728 例哮喘急诊就诊病例。使用加拿大环境部的固定监测站网络来估算该地区的每日空气污染水平。通过国家门诊护理报告系统(NACRS)识别急诊就诊。使用条件逻辑回归估计比值比及其 95%置信区间,并通过自然样条函数调整每日流感急诊就诊数量和天气变量的混杂影响。

结果

在温莎市,环境空气污染水平与哮喘急诊就诊之间存在统计学显著关联。在 4 月至 9 月期间,2 至 14 岁的儿童中,这种关联尤其明显。即,与 1 天滞后暴露于 SO2、NO2 和 CO 水平的四分位距增加相关,哮喘就诊的风险分别增加了 19%、25%和 36%。

结论

在温莎市,暴露于环境空气中的污染物会增加哮喘急诊就诊的风险,尤其是在儿童中。

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