Mihel Sandra, Milanović Sanja Musić
Croatian National Institute of Public Health, Zagreb, Croatia.
Coll Antropol. 2012 Jan;36 Suppl 1:183-8. doi: 10.5671/ca.2012361s.183.
Aim of this study was to investigate association of elevated body mass index and hypertension with general mortality in the cohort from Croatian Adult Health Cohort Study (CroHort). Risk of death according to body mass index (BMI) and blood pressure category, in period 2003/08, was calculated for 7,490 respondents, out of which 6,682 were alive and 808 were dead in 2008. Among men aged 65 and more, elevated BMI was associated with lower risk of death, in accordance with obesity paradox recorded in some previous studies which showed that older men with higher BMI have lower risk of death. Among women aged 50-64 years, being hypertensive was associated with increased risk of death compared to normotensive respondents. Despite obesity paradox which should be further explored, activities on primary and secondary prevention of excess weight and hypertension should be encouraged as means to prevent premature mortality in Croatian population.
本研究的目的是在克罗地亚成人健康队列研究（CroHort）的队列中，调查体重指数升高和高血压与全因死亡率之间的关联。根据体重指数（BMI）和血压类别，计算了2003/08年期间7490名受访者的死亡风险，其中2008年有6682人存活，808人死亡。在65岁及以上的男性中，BMI升高与较低的死亡风险相关，这与之前一些研究中记录的肥胖悖论一致，即BMI较高的老年男性死亡风险较低。在50 - 64岁的女性中，与血压正常的受访者相比，高血压与死亡风险增加相关。尽管肥胖悖论有待进一步探索，但应鼓励开展预防超重和高血压的一级和二级预防活动，作为预防克罗地亚人群过早死亡的手段。
