Dalfrà Maria Grazia, Busetto Luca, Chilelli Nino Cristiano, Lapolla Annunziata
Department of Medical and Surgical Sciences, Padova University, Padova, Italy.
J Matern Fetal Neonatal Med. 2012 Sep;25(9):1537-43. doi: 10.3109/14767058.2012.663829. Epub 2012 Mar 16.
It is well known that maternal obesity has adverse effects on the health of offspring, causing immediate and long-term morbidities. The various types of procedure coming under the heading of bariatric surgery have proved effective in preventing some maternal and foetal complications in morbidly obese pregnant women. This review aims to assess the role, the risks and the benefits of bariatric surgery for mothers and offspring. According to recent findings, pregnancy and neonatal outcomes in morbidly obese women who have undergone bariatric surgery depend to some extent on the type of surgery used. Maternal complications, nutritional defects and intestinal obstruction are more frequently reported after Roux-en-Y gastric bypass (RYGB) and biliopancreatic diversion (BPD) than after laparoscopic adjustable gastric banding (LAGB) procedures, whereas caesarean section, preterm delivery and neonatal death are more commonly reported after RYGB than after LAGB. The authors of the only long-term follow-up study conducted on this subject reported that the rate of obesity in the children dropped by 52% after bariatric surgery for the mother, and the cases of severe obesity decreased by 45%. Data on pregnancy and bariatric surgery confirm that the procedure is more effective than dietary measures alone in morbidly obese women, and that pregnancy outcome is generally favorable after surgery. Some studies have indicated, nonetheless, that pregnancies after bariatric surgery are at higher risk: the women affected require special medical attention, particularly as concerns gastrointestinal symptoms and vitamin deficiencies, warranting nutritional/dietary counselling by a multidisciplinary team before, during and after pregnancy.
众所周知,母亲肥胖会对后代健康产生不利影响,导致近期和长期发病。事实证明,各种减肥手术对预防病态肥胖孕妇的一些母婴并发症有效。本综述旨在评估减肥手术对母亲和后代的作用、风险及益处。根据最近的研究结果,接受减肥手术的病态肥胖女性的妊娠和新生儿结局在一定程度上取决于所采用的手术类型。与腹腔镜可调节胃束带术(LAGB)相比, Roux-en-Y胃旁路术(RYGB)和胆胰转流术(BPD)后更常报告母亲并发症、营养缺陷和肠梗阻,而RYGB后剖宫产、早产和新生儿死亡的报告比LAGB后更常见。关于这一主题的唯一一项长期随访研究的作者报告称,母亲接受减肥手术后,儿童肥胖率下降了52%,重度肥胖病例减少了45%。关于妊娠和减肥手术的数据证实,该手术对病态肥胖女性比单纯饮食措施更有效,且手术后妊娠结局总体良好。然而,一些研究表明,减肥手术后的妊娠风险更高:受影响的女性需要特别的医疗护理,尤其是在胃肠道症状和维生素缺乏方面,在妊娠前、妊娠期间和妊娠后需要多学科团队进行营养/饮食咨询。