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[莱蒂宁立体定向适配器:在立体定向条件下用于分次脑照射]

[Laitinen's stereo-adapter: application to the fractionated cerebral irradiation under stereotaxic conditions].

作者信息

Delannes M, Daly N, Bonnet J, Sabatier J, Trémoulet M

机构信息

Département de Radiothéraopie, Centre Claudius Régaud, Toulouse.

出版信息

Neurochirurgie. 1990;36(3):167-74; discussion 174-5.

PMID:2234260
Abstract

Radiosurgery is a technique which provides a single high dose of radiation very precisely to an intracranial lesion. The volume of tissue treated is small enough to avoid undue biological damage. This treatment requires very sophisticated apparatus and often considerable modifications in the treatment apparatus. The authors have closen to elaborate a system which makes it possible to deliver conventional fractionated irradiation, using a non-invasive stereotactic head frame called "Laitinen stereo-adapter". By fractionating the dose, most benign or low-grade malignant brain tumours can be treated, whatever their volume. The stereo-adapter and the target localization process are described. It can be used with C.T. scanning, angiography or M.R.I. The treatment apparatus is a linear accelerator delivering a 10 M.V. photon beam and treatment is made in the precise positioning of the target localization. The geometrical accuracy of the repeated mountings was studied in a preliminary study, showing a mean discrepancy of less than 1 mm in the three space planes. The geometrical accuracy of the radiation treatment was also studied on a phantom and the precision evaluated at less than 1 mm. The addition of extra collimators with a precollimation system decreased the lateral penumbra to 2-3 mm. Careful dosimetry was performed for each collimator. The use of non-coplanar arcs makes it possible to obtain a steep dose fall off outside the target volume. The dose planning calculations were compared to photodensitometry and thermoluminescent measurements, showing a good correlation. Each technical point will be discussed.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

放射外科是一种能够非常精确地向颅内病变提供单次高剂量辐射的技术。所治疗的组织体积小到足以避免过度的生物损伤。这种治疗需要非常精密的设备,并且通常需要对治疗设备进行相当大的改装。作者选择精心设计一种系统,该系统使用一种名为“莱蒂宁立体适配器”的非侵入性立体定向头架来进行传统的分次照射。通过分次给予剂量,可以治疗大多数良性或低度恶性脑肿瘤,无论其体积大小。本文描述了立体适配器和靶点定位过程。它可与CT扫描、血管造影或MRI一起使用。治疗设备是一台能产生10兆伏光子束的直线加速器,治疗是在靶点定位的精确定位下进行的。在一项初步研究中对重复安装的几何精度进行了研究,结果表明在三个空间平面上平均偏差小于1毫米。还在体模上研究了放射治疗的几何精度,并评估其精度小于1毫米。增加带有预准直系统的额外准直器可将侧向半值层减小到2 - 3毫米。对每个准直器都进行了仔细的剂量测定。使用非共面弧可以在靶体积之外获得陡峭的剂量下降。将剂量规划计算结果与光密度测定法和热释光测量结果进行了比较,显示出良好的相关性。每个技术要点都将进行讨论。(摘要截选至250字)

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