Williams D H, Levin H S, Eisenberg H M
Division of Neurosurgery, University of Texas Medical Branch, Galveston.
Neurosurgery. 1990 Sep;27(3):422-8. doi: 10.1097/00006123-199009000-00014.
Inconsistencies across studies concerning outcome after mild head injury may reflect differences in the diagnostic criteria used for selection of patients. Consequently, we compared the neurobehavioral outcome in three groups of consecutively hospitalized patients (aged 16 to 50 years) who sustained a closed head injury (CHI) and had a Glasgow Coma Scale (GCS) score in the 9 to 15 range. These groups included patients with uncomplicated CHI with mild impairment of consciousness as reflected by a GCS score in the 13 to 15 range (n = 78), patients with initially mild impairment of consciousness complicated by brain lesion or depressed skull fracture (n = 77), and patients with moderate CHI (n = 60). Tests of memory, information processing, and verbal fluency were administered within 1 to 3 months after injury, and the Glasgow Outcome Scale was completed at 6 months. Neurobehavioral functioning was impaired in the groups with complicated mild CHI and moderate CHI as compared to the group with uncomplicated mild CHI. Although moderate CHI produced longer durations of impaired consciousness and posttraumatic amnesia than complicated mild head injury, patients in these groups did not differ in neurobehavioral performance. Global outcome at 6 months was better in the patients with mild CHI than in patients with complicated mild and moderate injuries. Analysis of the various complications of mild CHI revealed that the presence of an intracranial lesion was related to more severe neurobehavioral sequelae than injuries complicated by a depressed fracture.
关于轻度头部损伤后结果的研究存在不一致性,这可能反映了用于患者选择的诊断标准存在差异。因此,我们比较了三组连续住院患者(年龄在16至50岁之间)的神经行为结果,这些患者均遭受了闭合性头部损伤(CHI),且格拉斯哥昏迷量表(GCS)评分为9至15分。这些组包括:GCS评分为13至15分,意识轻度受损的单纯CHI患者(n = 78);最初意识轻度受损,并发脑损伤或颅骨凹陷性骨折的患者(n = 77);以及中度CHI患者(n = 60)。在受伤后1至3个月内进行记忆、信息处理和语言流畅性测试,并在6个月时完成格拉斯哥预后量表评估。与单纯轻度CHI组相比,并发轻度CHI组和中度CHI组的神经行为功能受损。尽管中度CHI导致意识障碍和创伤后遗忘的持续时间比并发轻度头部损伤更长,但这些组患者的神经行为表现并无差异。轻度CHI患者6个月时的总体预后优于并发轻度和中度损伤的患者。对轻度CHI各种并发症的分析显示,颅内病变的存在比颅骨凹陷性骨折并发损伤导致更严重的神经行为后遗症。