Department of Chemistry, University of Kansas, Kansas, USA.
Photochem Photobiol Sci. 2012 Mar;11(3):472-88. doi: 10.1039/c2pp05399c. Epub 2012 Feb 16.
Most applications of photoremovable protecting groups have used o-nitrobenzyl compounds and their (often commercially available) derivatives that, however, have several disadvantages. The focus of this review is on applications of the more recently developed title compounds, which are especially well suited for time-resolved biochemical and physiological investigations, because they release the caged substrates in high yield within a few nanoseconds or less. Together, these two chromophores cover the action spectrum for photorelease from >700 nm to 250 nm.
大多数光脱保护基团的应用都使用了邻硝基苄基化合物及其（通常可商购的）衍生物，但这些化合物存在几个缺点。本综述的重点是最近开发的标题化合物的应用，这些化合物特别适合于时间分辨的生化和生理研究，因为它们可以在几纳秒或更短的时间内以高收率释放被保护的底物。这两个生色团一起覆盖了从>700nm 到 250nm 的光释放作用光谱。
