State Key Laboratory of Microbial Technology, Shandong University, Jinan, People’s Republic of China.
Appl Environ Microbiol. 2012 May;78(9):3480-3. doi: 10.1128/AEM.00058-12. Epub 2012 Feb 17.
NAD-dependent l- and d-lactate dehydrogenases coexist in Lactobacillus genomes and may convert pyruvic acid into l-lactic acid and d-lactic acid, respectively. Our findings suggest that the relative catalytic efficiencies of ldhL- and ldhD-encoded products are crucial for the optical purity of lactic acid produced by Lactobacillus strains.
NAD 依赖性的 l-和 d-乳酸脱氢酶共存于乳杆菌基因组中,分别将丙酮酸转化为 l-乳酸和 d-乳酸。我们的研究结果表明,ldhL 和 ldhD 编码产物的相对催化效率对乳酸杆菌菌株产生的乳酸的光学纯度至关重要。