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植物化学和 Ochna 属植物的生物学研究。

Phytochemical and biological studies of Ochna species.

机构信息

Institute of Bioconvergence Technology, Dongguk University, Gyeongju 780714, Republic of Korea.

出版信息

Chem Biodivers. 2012 Feb;9(2):251-71. doi: 10.1002/cbdv.201100164.

DOI:10.1002/cbdv.201100164
PMID:22344903
Abstract

The genus Ochna L. (Gr, Ochne; wild pear), belonging to the Ochnaceae family, includes ca. 85 species of evergreen trees, shrubs, and shrublets, distributed in tropical Asia, Africa, and America. Several members of this genus have long been used in folk medicine for treatment of various ailments, such as asthma, dysentery, epilepsy, gastric disorders, menstrual complaints, lumbago, ulcers, as an abortifacient, and as antidote against snake bites. Up to now, ca. 111 constituents, viz. flavonoids (including bi-, tri-, and pentaflavonoids), anthranoids, triterpenes, steroids, fatty acids, and a few others have been identified in the genus. Crude extracts and isolated compounds have been found to exhibit analgesic, anti-HIV-1, anti-inflammatory, antimalarial, antimicrobial, and cytotoxic activities, lending support to the rationale behind several of its traditional uses. The present review compiles the informations concerning the traditional uses, phytochemistry, and biological activities of Ochna.

摘要

Ochna L. 属(Gr,Ochne;野梨),属于 Ochnaceae 科,包括约 85 种常绿乔木、灌木和小灌木,分布于热带亚洲、非洲和美洲。该属的一些成员长期以来一直被民间医学用于治疗各种疾病,如哮喘、痢疾、癫痫、胃病、月经不调、腰痛、溃疡、堕胎和抗蛇毒。迄今为止,已在该属中鉴定出约 111 种成分,如类黄酮(包括二、三、五倍体类黄酮)、蒽醌、三萜、甾体、脂肪酸和其他一些成分。粗提取物和分离的化合物已被发现具有镇痛、抗 HIV-1、抗炎、抗疟、抗菌和细胞毒性活性,支持了其几种传统用途背后的原理。本综述汇集了有关 Ochna 的传统用途、植物化学和生物活性的信息。

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