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体力活动、吸烟和饮酒与欧洲、南亚或非洲裔人群心血管疾病相关住院的关系。

Association of physical activity, smoking, and alcohol intake with CVD-related hospital discharge in people of European, South Asian, or African descent.

机构信息

Academic Medical Center, University of Amsterdam, The Netherlands.

出版信息

Eur J Prev Cardiol. 2013 Feb;20(1):80-8. doi: 10.1177/2047487311434232. Epub 2012 Jan 6.

DOI:10.1177/2047487311434232
PMID:22345676
Abstract

BACKGROUND

It is unclear whether the beneficial effects of certain lifestyle factors are equally strong in ethnic minority populations in Europe. This study explores whether this association of physical activity, smoking, and alcohol intake with cardiovascular disease (CVD)-related hospital discharge differs among South Asian Surinamese, African Surinamese, or Dutch descent living in the Netherlands.

DESIGN

Prospective cohort.

METHODS

We obtained baseline data from 370 South Asian, 689 African, and 567 Dutch participants (aged 35-60 years) of the SUNSET study (2001-2003). Follow up ended in December 2007. We used Cox proportional hazards models to study the associations of lifestyle factors with CVD-related hospital discharge.

RESULTS

In the overall study population, low amount of physical activity (hazard ratio, HR 1.88, 95% CI 1.23-2.86), current smoking (HR 1.63, 95% CI 1.20-2.22), and nondrinking (HR 1.52, 95% CI 1.04-2.23) were associated with CVD-related hospital admission. There was no statistically significant effect of ethnicity on these associations. For instance, the adjusted HR for CVD-related hospital discharge regarding a low amount of physical activity was 2.77 (95% CI 1.31-5.87) for Africans, 1.53 (95% CI 0.76-3.05) for South Asians, and 1.55 (95% CI 0.73-3.30) for the Dutch. The p-value for ethnicity by lifestyle interaction was 0.41.

CONCLUSION

We did not find a different association across ethnic groups of South Asian Surinamese, African Surinamese, or Dutch descent between physical activity, smoking, and alcohol intake and 5-year hazard of a CVD-related hospital discharge. We recommend confirmation in multiethnic studies in other contexts.

摘要

背景

目前尚不清楚某些生活方式因素对欧洲少数民族人群的有益影响是否同样强烈。本研究旨在探讨生活方式因素(包括体力活动、吸烟和饮酒)与心血管疾病(CVD)相关住院之间的关联在荷兰的南亚苏里南人、非洲苏里南人和荷兰裔人群中是否存在差异。

设计

前瞻性队列研究。

方法

我们获取了来自 SUNSET 研究(2001-2003 年)的 370 名南亚人、689 名非洲人和 567 名荷兰人(年龄 35-60 岁)的基线数据。随访于 2007 年 12 月结束。我们使用 Cox 比例风险模型研究生活方式因素与 CVD 相关住院之间的关系。

结果

在整个研究人群中,低体力活动量(危险比 1.88,95%置信区间 1.23-2.86)、当前吸烟(危险比 1.63,95%置信区间 1.20-2.22)和非饮酒(危险比 1.52,95%置信区间 1.04-2.23)与 CVD 相关住院有关。种族对这些关联没有统计学上显著的影响。例如,对于低体力活动量与 CVD 相关住院的调整后的危险比,非洲人为 2.77(95%置信区间 1.31-5.87),南亚人为 1.53(95%置信区间 0.76-3.05),荷兰人为 1.55(95%置信区间 0.73-3.30)。种族与生活方式相互作用的 p 值为 0.41。

结论

我们没有发现南亚苏里南人、非洲苏里南人和荷兰裔人群在体力活动、吸烟和饮酒与 CVD 相关住院 5 年风险之间存在不同的关联。我们建议在其他背景下的多民族研究中进行证实。

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