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心血管危险因素在中等收入国家的聚集:紧急呼吁。

Clustering of cardiovascular risk factors in a middle-income country: a call for urgency.

机构信息

Clinical Research Centre, Ministry of Health, Malaysia.

出版信息

Eur J Prev Cardiol. 2013 Apr;20(2):368-75. doi: 10.1177/2047487312437327. Epub 2012 Jan 24.

Abstract

BACKGROUND

This study aimed to estimate the prevalence of cardiovascular risk factors and its clustering. The findings are to help shape the Malaysian future healthcare planning for cardiovascular disease prevention and management.

METHODS

Data from a nationally representative cross-sectional survey was used. The survey was conducted via a face-to-face interview using a standardised questionnaire. A total of 37,906 eligible participants aged 18 years and older was identified, of whom 34,505 (91%) participated. Focus was on hypertension, hyperglycaemia (diabetes and impaired fasting glucose), hypercholesterolaemia and central obesity.

RESULTS

Overall, 63% (95% confidence limits 62, 65%) of the participants had at least one cardiovascular risk factor, 33% (32, 35%) had two or more and 14% (12, 15%) had three risk factors or more. The prevalence of hypertension, hyperglycaemia, hypercholesterolaemia and central obesity were 38%, 15%, 24% and 37%, respectively. Women were more likely to have a higher number of cardiovascular risk factors for most age groups; adjusted odds ratios ranging from 1.1 (0.91, 1.32) to 1.26 (1.12, 1.43) for the presence of one risk factor and 1.07 (0.91, 1.32) to 2.00 (1.78, 2.25) for two or more risk factors.

CONCLUSIONS

Cardiovascular risk-factor clustering provides a clear impression of the true burden of cardiovascular disease risk in the population. Women displayed higher prevalence and a younger age shift in clustering was seen. These findings signal the presence of a cardiovascular epidemic in an upcoming middle-income country and provide evidence that drastic measures have to be taken to safeguard the health of the nation.

摘要

背景

本研究旨在估计心血管危险因素的流行率及其聚集情况。研究结果将有助于为马来西亚未来的心血管疾病预防和管理制定医疗保健计划。

方法

本研究使用了一项全国代表性的横断面调查数据。该调查通过面对面访谈和使用标准化问卷进行。共确定了 37906 名年龄在 18 岁及以上的合格参与者,其中 34505 名(91%)参与者完成了调查。研究重点关注高血压、高血糖(糖尿病和空腹血糖受损)、高胆固醇血症和中心性肥胖。

结果

总体而言,63%(95%置信区间 62,65%)的参与者至少存在一种心血管危险因素,33%(32,35%)存在两种或更多种,14%(12,15%)存在三种或更多种危险因素。高血压、高血糖、高胆固醇血症和中心性肥胖的患病率分别为 38%、15%、24%和 37%。大多数年龄组的女性更有可能存在更多数量的心血管危险因素;存在一种危险因素的调整优势比范围为 1.1(0.91,1.32)至 1.26(1.12,1.43),存在两种或更多种危险因素的调整优势比为 1.07(0.91,1.32)至 2.00(1.78,2.25)。

结论

心血管危险因素聚集清楚地反映了人群中心血管疾病风险的真实负担。女性表现出更高的患病率和更年轻的年龄分布变化。这些发现表明,一个即将到来的中等收入国家存在心血管疾病流行,这表明必须采取严厉措施来维护国家的健康。

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