Hammoudeh Ayman J, Alhaddad Imad A, Khader Yousef, Tabbalat Ramzi, Al-Mousa Eyas, Saleh Akram, Jarrah Mohamad, Nammas Assem, Izraiq Mahmoud
Cardiology Department, Istishari Hospital, Amman, Jordan.
Cardiology Department, Jordan Hospital, Amman, Jordan.
J Saudi Heart Assoc. 2017 Jul;29(3):195-202. doi: 10.1016/j.jsha.2016.10.002. Epub 2016 Oct 20.
Cardiovascular disease (CVD) is the leading cause of death in the Middle East. We sought to study the prevalence and coexistence of 6 cardiovascular risk factors (RFs) among patients who underwent percutaneous coronary intervention (PCI), and to evaluate the impact of age and gender on the presence of multiple RFs.
In this prospective, multicenter study, 2426 consecutive patients were enrolled. Mean age was 59.0 ± 10.1 years and 500 (20.6%) were women. Acute coronary syndrome and stable coronary disease were the indications for PCI in 77.1% and 22.9%, respectively. Hypertension was present in 62.3%, diabetes in 53.8%, hypercholesterolemia in 48.8%, smoking in 43.5%, family history of premature CVD 39.4% and obesity in 28.8%. Only 3.8% did not have any of these RFs. Presence of ⩾3 and ⩾4 RFS was observed in 57.4% and 29.5% of patients, respectively. Presence of ⩾3 RFs was more common in women than men (69.0% vs. 54.5%, < 0.0001), and among patients 41-65 years of age than older or younger patients (60.1% vs. 52.0% vs. 48.3%, respectively, = 0.017). Cardiovascular RFs are highly prevalent in this PCI Middle Eastern population undergoing PCI. More than half and more than one-fourth of the patients had at least 3 or 4 RFs; respectively. More women than men and more middle aged patients than older or younger patients had significantly higher rates of presence of multiple RFs.
心血管疾病(CVD)是中东地区的主要死因。我们试图研究接受经皮冠状动脉介入治疗(PCI)的患者中6种心血管危险因素(RFs)的患病率及共存情况,并评估年龄和性别对多种RFs存在情况的影响。
在这项前瞻性多中心研究中,连续纳入了2426例患者。平均年龄为59.0±10.1岁,女性500例(20.6%)。急性冠状动脉综合征和稳定型冠心病分别是77.1%和22.9%患者接受PCI的指征。高血压患病率为62.3%,糖尿病为53.8%,高胆固醇血症为48.8%,吸烟为43.5%,早发性CVD家族史为39.4%,肥胖为28.8%。只有3.8%的患者没有这些RFs中的任何一种。分别有57.4%和29.5%的患者存在≥3种和≥4种RFs。≥3种RFs在女性中比男性更常见(69.0%对54.5%,P<0.0001),在41 - 65岁的患者中比年龄较大或较小的患者更常见(分别为60.1%对52.0%对48.3%,P = 0.017)。在接受PCI的中东人群中,心血管RFs非常普遍。超过一半和超过四分之一的患者分别至少有3种或4种RFs。女性比男性以及中年患者比年龄较大或较小的患者有多种RFs的比例显著更高。