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1991-1994 年至 2010-2012 年期间,德里国家首都辖区城乡居民冠心病及其危险因素的流行率变化。

Change in prevalence of Coronary Heart Disease and its risk between 1991-94 to 2010-12 among rural and urban population of National Capital Region, Delhi.

机构信息

Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi, India.

Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian Heart J. 2020 Sep-Oct;72(5):403-409. doi: 10.1016/j.ihj.2020.08.008. Epub 2020 Aug 9.

Abstract

OBJECTIVES

We aimed to measure the change in prevalence of Coronary Heart Disease (CHD) and Cardiovascular Diseases (CVDs) risk among those aged 35-64 years in urban and rural areas of National Capital Region (NCR) of Delhi, between 1991-1994 (survey 1) and 2010-2012 (survey 2).

METHODS

Both surveys used similar sampling methodology and mean ages of participants were similar. A total of 3048 and 2052 subjects were studied in urban Delhi and 2487 and 1917 participants recruited from rural Ballabgarh in survey 1 and in survey 2 respectively. CHD was diagnosed based on a Minnesota coded ECG and Rose angina questionnaire. Data on behavioural, physical, clinical and biochemical parameters were collected using standard methods. CVD Risk of participants was calculated using the gender specific Framingham risk equation.

RESULTS

The age and sex standardised prevalence of CHD in urban Delhi increased from 10.3% (95% CI: 9.2-11.4) to 14.1% (95% CI: 12.6-15.6) between the two surveys as compared to an increase from 6.0% (95% CI: 5.0-6.9) to 7.4% (95% CI: 6.3-8.6) in rural Ballabgarh. The highest increase in the prevalence of CHD was reported among urban women (10.1% to 16.6%).The proportion of population with high 10-year CVD risk increased to 4.1% from 1.2% in rural areas as compared to 4.8% from 2.5% in urban areas.

CONCLUSIONS

The CHD and CVD risk has increased over 20 years period in and around Delhi and the increase was more in rural population and women, traditionally considered to be at low risk.

摘要

目的

本研究旨在衡量在德里国家首都辖区(NCR)城乡地区,年龄在 35-64 岁之间的人群中心血管疾病(CVD)和冠心病(CHD)发病率的变化,该研究比较了 1991-1994 年(调查 1)和 2010-2012 年(调查 2)的数据。

方法

这两项研究均采用了相似的抽样方法,且参与者的平均年龄相似。在调查 1 中,共纳入了 3048 名来自城市德里的研究对象和 2487 名来自农村巴拉巴格的研究对象;在调查 2 中,共纳入了 2052 名来自城市德里的研究对象和 1917 名来自农村巴拉巴格的研究对象。CHD 的诊断基于明尼苏达州编码心电图和 Rose 心绞痛问卷。采用标准方法收集参与者的行为、身体、临床和生化参数数据。采用性别特异性弗雷明汉风险方程计算参与者的 CVD 风险。

结果

与农村巴拉巴格相比,城市德里的 CHD 发病率在年龄和性别标准化后,从调查 1 中的 10.3%(95%CI:9.2-11.4)增加到调查 2 中的 14.1%(95%CI:12.6-15.6);农村巴拉巴格的 CHD 发病率从调查 1 中的 6.0%(95%CI:5.0-6.9)增加到调查 2 中的 7.4%(95%CI:6.3-8.6)。CHD 发病率的增幅最大的是城市女性(从 10.1%增加到 16.6%)。农村地区 10 年 CVD 高危人群的比例从 1.2%增加到 4.1%,而城市地区的这一比例从 2.5%增加到 4.8%。

结论

在过去 20 年中,德里及其周边地区的 CHD 和 CVD 风险呈上升趋势,农村地区和女性的增幅更大,而女性传统上被认为是低危人群。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eec/7670492/7cf22644da42/gr1.jpg

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