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心血管危险因素的流行与聚集:中国南京成年人的横断面调查。

Prevalence and clustering of cardiovascular risk factors: a cross-sectional survey among Nanjing adults in China.

机构信息

Department of Non-communicable Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China.

Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.

出版信息

BMJ Open. 2018 Jun 14;8(6):e020530. doi: 10.1136/bmjopen-2017-020530.

Abstract

OBJECTIVES

To estimate prevalence and clustering of cardiovascular risk factors (CRFs), and investigate the association between relevant characteristics and CRF clustering among adults in eastern China.

DESIGN

Community-based cross-sectional study.

SETTING

Data were collected by interview survey, physical measurements and laboratory examinations from the 2011 Nanjing Chronic Disease and Risk Factor Surveillance.

PARTICIPANTS

A representative sample of 41 072 residents aged ≥18 years volunteered to participate in the survey, with a response rate of 91.3%. We excluded 1232 subjects due to missing data or having a history of cardiovascular diseases; a total of 39 840 participants were included in the analysis.

OUTCOME MEASURES

Prevalence and clustering of five major CRFs including hypertension, diabetes, dyslipidaemia, overweight or obesity and current smoking.

RESULTS

Of 39 840 participants (mean age 47.9±16.2 years), 17 964 (45.1%) were men and 21 876 (54.9%) were women. The weighted prevalence of CRFs ranged between 6.2% for diabetes and 35.6% for overweight or obesity. The proportion of CRFs tended to be higher in men, the elderly, participants who lost a life partner, or lived in rural areas, or had lower level of education and total annual income. Overall, 30.1% and 35.2% of participants had one and at least two CRFs, respectively. Multivariate logistic regression revealed that men, older age, loss of a life partner, lower level of socioeconomic status, rural areas, insufficient physical activity or unhealthy diets were positively associated with CVD risk factor clustering, compared with their counterparts.

CONCLUSIONS

High regional prevalence of hypertension, dyslipidaemia, overweight or obesity and their clustering are present in Nanjing. The Nanjing government should develop effective public health policies at the regional level especially for high-risk groups, such as enhancing the public's health awareness, organising health promotion programmes, implementing smoke-free law, producing healthy nutrient foods, providing free or low-cost public sports and fitness facilities.

摘要

目的

评估中国东部成年人心血管危险因素(CRFs)的流行率和聚集情况,并探讨相关特征与 CRF 聚集之间的关系。

设计

基于社区的横断面研究。

地点

数据来自 2011 年南京慢性病及危险因素监测的问卷调查、体格检查和实验室检查。

参与者

共有 41072 名年龄≥18 岁的居民自愿参加了调查,应答率为 91.3%。我们排除了 1232 名因数据缺失或有心血管疾病史而无法入组的对象;共有 39840 名参与者纳入分析。

结局测量

包括高血压、糖尿病、血脂异常、超重或肥胖和当前吸烟在内的 5 大主要 CRFs 的流行率和聚集情况。

结果

在 39840 名参与者(平均年龄 47.9±16.2 岁)中,男性 17964 人(45.1%),女性 21876 人(54.9%)。CRFs 的加权流行率范围在糖尿病的 6.2%至超重或肥胖的 35.6%之间。男性、老年人、失去生活伴侣的参与者、农村地区居民、教育程度和总收入较低的参与者,CRFs 的比例较高。总体而言,分别有 30.1%和 35.2%的参与者有 1 种和至少 2 种 CRFs。多变量 logistic 回归显示,与相应的对照相比,男性、年龄较大、失去生活伴侣、社会经济地位较低、农村地区、体力活动不足或饮食不健康与 CVD 危险因素聚集呈正相关。

结论

南京地区高血压、血脂异常、超重或肥胖的区域性流行率较高,且存在聚集情况。南京政府应在区域层面制定有效的公共卫生政策,特别是针对高危人群,如提高公众的健康意识、组织健康促进计划、实施禁烟法、生产健康营养食品、提供免费或低成本的公共体育和健身设施。

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