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Choroid plexus carcinoma in an adult.

作者信息

Kishore Sanjeev, Negi Gita, Meena Harsh, Anuradha Kusum, Pathak Prakash Ved, Bansal Kk

机构信息

Department of Pathology, Sri Guru Ram Rai Medical College, Dehradun, Uttarakhand, India.

出版信息

J Neurosci Rural Pract. 2012 Jan;3(1):71-3. doi: 10.4103/0976-3147.91952.

DOI:10.4103/0976-3147.91952
PMID:22346199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3271623/
Abstract

Choroid plexus carcinoma is a very rare tumor in adults. Here we report a rare case of choroid plexus carcinoma in an adult patient. A 24-year-old male presented with a right temporal intraventricular tumor with a cystic component also extending up to the cortex. Histological examination revealed complex papillary structures and glandular spaces showing stratification and multilayering of cells with nuclear crowding and numerous mitotic figures and large areas of necrosis. The patient went through a complete search for a possible primary keeping in mind the differential diagnosis of metastatic carcinoma that is more common in adults but there was no evidence of any other tumor. Finally a diagnosis of choroid plexus carcinoma was rendered. Immunohistochemical analysis for p53 protein showed positivity. Choroid plexus carcinoma is exceptionally rare in adults but cases do occur.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab57/3271623/d240d08916d7/JNRP-3-71-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab57/3271623/1e60033cbbae/JNRP-3-71-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab57/3271623/ecc2aa34336e/JNRP-3-71-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab57/3271623/b313cacc7007/JNRP-3-71-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab57/3271623/e4253d070b57/JNRP-3-71-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab57/3271623/d240d08916d7/JNRP-3-71-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab57/3271623/1e60033cbbae/JNRP-3-71-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab57/3271623/ecc2aa34336e/JNRP-3-71-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab57/3271623/b313cacc7007/JNRP-3-71-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab57/3271623/e4253d070b57/JNRP-3-71-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab57/3271623/d240d08916d7/JNRP-3-71-g005.jpg

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本文引用的文献

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Neurol India. 2008 Apr-Jun;56(2):179-81. doi: 10.4103/0028-3886.41997.
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Choroid plexus carcinoma.脉络丛癌
Arch Pathol Lab Med. 2008 Aug;132(8):1350-4. doi: 10.5858/2008-132-1350-CPC.
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Solitary choroid plexus metastasis from carcinoma of the oesophagus.食管癌细胞的孤立性脉络丛转移
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Rare variant associated with Li-Fraumeni syndrome exhibits variable penetrance in a Saudi family.与李-佛美尼综合征相关的罕见变异在一个沙特家庭中表现出可变外显率。
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Malignant progression in choroid plexus papillomas.脉络丛乳头状瘤的恶性进展
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Rhabdoid choroid plexus carcinoma: a rare histological type.
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Identification of five new families strengthens the link between childhood choroid plexus carcinoma and germline TP53 mutations.五个新家族的鉴定加强了儿童脉络丛癌与种系TP53突变之间的联系。
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