Proctor E M, Banerjee S N
Division of Medical Microbiology, Department of Pathology, University of British Columbia;
Can J Infect Dis. 1994 Sep;5(5):218-23. doi: 10.1155/1994/586810.
To determine the seroprevalence of toxoplasmosis in vegetarian and nonvegetarian members of different ethnic communities in the lower Fraser Valley of British Columbia.
Serum samples were collected from 2027 participants drawn from various ethnic groups and tested by elisa for the presence of immunoglobulin (Ig) G and IgM antibodies to Toxoplasma gondii. Coded questionnaires requesting information relevant to the study were completed by each participant. The study population comprised 1334 females and 693 males; ages ranged from 17 to 102 years.
Four hundred and nineteen (20.7%) individuals were IgG positive with titres ranging from 1:100 to 1:3200. IgM antibodies were detected in only four individuals. The seroprevalence rose with increase in age but there was no significant difference between males and females. A positive correlation was shown between ingestion of meat and between consumption of unpasteurized milk and antibodies to T gondii. Eighty per cent of females between the ages of 17 and 40, of all ethnic origins, were seronegative. Seropositivity did not differ between cat owners and non-cat owners.
Women of childbearing age are at risk of acquiring toxoplasmosis during pregnancy and of transmitting the infection transplacentally. Consumption of undercooked meat and unpasteurized milk may result in the acquisition of toxoplasmosis. Data suggest that acquisition of toxoplasmosis is more likely via environmental oocysts or cysts in food source animals than by direct contact with cats.
确定不列颠哥伦比亚省低弗雷泽河谷不同种族社区素食者和非素食者弓形虫病的血清流行率。
从2027名来自不同种族的参与者中采集血清样本，并用酶联免疫吸附测定法检测抗刚地弓形虫免疫球蛋白（Ig）G和IgM抗体的存在。每位参与者都填写了要求提供与研究相关信息的编码问卷。研究人群包括1334名女性和693名男性；年龄在17至102岁之间。
419人（20.7%）IgG呈阳性，滴度范围为1:100至1:3200。仅在4人身上检测到IgM抗体。血清流行率随年龄增长而上升，但男女之间无显著差异。食用肉类以及饮用未杀菌牛奶与抗刚地弓形虫抗体之间呈正相关。所有种族背景的17至40岁女性中，80%血清学检测呈阴性。养猫者和非养猫者的血清阳性率无差异。
育龄妇女在怀孕期间有感染弓形虫病并经胎盘传播感染的风险。食用未煮熟的肉类和未杀菌牛奶可能导致感染弓形虫病。数据表明，感染弓形虫病更可能是通过食物源动物中的环境卵囊或包囊，而非与猫直接接触。
