Sacks J J, Roberto R R, Brooks N F
JAMA. 1982 Oct 8;248(14):1728-32. doi: 10.1001/jama.1982.03330140038029.
In October 1978, a large family cluster of acute toxoplasmosis was identified in northern California. Indirect fluorescent IgM antibody tests showed that ten of 24 members of an extended family had serological evidence of acute Toxoplasma infection. The index case had retinochoroiditis; the other nine persons had asymptomatic infections. All ten seropositive persons had recently consumed raw goat's milk from the family herd as compared with no consumption of raw milk by the 14 persons with negative results. No dietary item or other risk factors were as strongly associated with positive serological test results as raw milk consumption. Although ingestion of soil-transmitted oocysts could not be ruled out unequivocally as the source of infection, the data suggest that drinking raw milk from infected goats might be another possible vehicle for the transmission of toxoplasmosis.
1978年10月，在加利福尼亚州北部发现了一大户人家集体感染急性弓形虫病的病例。间接荧光IgM抗体检测显示，一个大家庭的24名成员中有10人有急性弓形虫感染的血清学证据。索引病例患有视网膜脉络膜炎；其他9人有无症状感染。与14名检测结果为阴性的人未饮用生牛奶相比，所有10名血清反应阳性的人最近都饮用了自家畜群产的生山羊奶。没有任何饮食项目或其他风险因素与血清学检测阳性结果的关联程度能像饮用生牛奶那样强。虽然不能完全排除摄入经土壤传播的卵囊作为感染源的可能性，但数据表明，饮用受感染山羊的生牛奶可能是弓形虫病传播的另一个可能途径。
