Department of Gynecology and Obstetrics, Baskent University, Konya, Turkey.
Department of Microbiology, Educational and Research Hospital, Karabuk University, Karabuk, Turkey.
J Obstet Gynaecol. 2021 Jul;41(5):714-720. doi: 10.1080/01443615.2020.1789954. Epub 2020 Oct 12.
() infection causes serious problems leading to maternal complications and foetal anomalies during pregnancy. The aim of this study was to identify risk factors for toxoplasmosis and to determine the seroprevalence of the disease with regard to the awareness levels of patients. A total of 214 pregnant women who were admitted to Karabuk University, Gynaecology and Obstetrics Clinic between July 2018 and November 2018 and accepted to participate were included this cross-sectional study. Venous blood samples were obtained and anti- IgG and IgM levels were analysed. The demographic characteristics of the patients were recorded and a questionnaire investigating about risk factors were completed. The relationship between toxoplasmosis and risk factors was evaluated using multivariate regression analysis. The prevalence of toxoplasmosis among the pregnant women was 14% (35/214). The potential risk factors of toxoplasmosis were primigravidity (AOR = 2.56 95% CI: [1.26-8.26]), cat ownership (AOR = 10.29, 95% CI: [3.58-29.60]), and sausage/salami consumption (AOR = 2.96, 95%CI: [2.10-7.46]);22.4% of the women were aware of toxoplasmosis, and awareness was significantly higher in multigravida women compared with primigravida women (=.042). Congenital toxoplasmosis can be prevented through pregnancy screening programmes and education aimed at increasing awareness and protection.IMPACT STATEMENT The seroprevalence of toxoplasmosis is very variable and may differ significantly between countries, and even different geographic regions of the same country. Raising awareness of the disease among persons in risk groups through education is a primary objective in prevention. seropositivity was found to be related with being primigravid, cat ownership and having close contact with cats, and consumption of meat products such as salami and sausages. In addition, primigravidity is a risk factor for toxoplasmosis because the awareness of the disease was lower than in multiparous women. It should also be known that women of childbearing age are in the high-risk group for toxoplasmosis, and studies on preventive measures should be performed. Increased awareness can prevent infection and the possibility of complications due to congenital toxoplasmosis, especially in the reproductive period of women.
()感染会导致严重的问题,导致孕妇出现并发症和胎儿畸形。本研究的目的是确定弓形体病的危险因素,并确定该疾病的血清流行率,以及患者的知晓率。
本横断面研究共纳入 214 名 2018 年 7 月至 11 月期间在卡拉比克大学妇产科诊所就诊并同意参与的孕妇。采集静脉血样,分析抗 IgG 和 IgM 水平。记录患者的人口统计学特征,并完成一份关于危险因素的调查问卷。采用多变量回归分析评估弓形体病与危险因素的关系。
孕妇弓形体病的患病率为 14%(35/214)。弓形体病的潜在危险因素为初产妇(AOR = 2.56 95%CI:[1.26-8.26])、养猫(AOR = 10.29 95%CI:[3.58-29.60])和食用香肠/萨拉米(AOR = 2.96,95%CI:[2.10-7.46]);22.4%的女性了解弓形体病,多产妇的知晓率明显高于初产妇(= 0.042)。
通过妊娠筛查计划和旨在提高认识和保护的教育,可以预防先天性弓形体病。
本研究表明,弓形体病的血清流行率差异很大,在不同国家甚至同一国家的不同地理区域可能有很大差异。通过教育提高高危人群对该病的认识是预防的主要目标。血清阳性与初产妇、养猫和与猫密切接触以及食用香肠和萨拉米等肉类产品有关。此外,初产妇是弓形体病的一个危险因素,因为她们对该病的认识低于多产妇。还应该知道,育龄妇女处于弓形体病的高危人群,应该开展预防措施的研究。提高认识可以预防感染和先天性弓形体病引起的并发症的可能性,尤其是在女性的生育期。