Chu Nain-Feng, Chin Hsien-Chuan, Wang Shu-Chuan
Department of Community Medicine, Shuang-Ho Hospital, Taipei Medical University, Taipei, Taiwan.
ISRN Cardiol. 2011;2011:743640. doi: 10.5402/2011/743640. Epub 2011 Jul 13.
Background. To evaluate the prevalence and the importance of anthropometric indexes on metabolic syndrome (MetS) among young adolescents in Taiwan. Methods. We conducted a cross sectional survey to obtain a representative sampling among Taipei adolescents in 2003, totally enrolled of 1,562 adolescents (764 boys and 798 girls) from age 11 to 15. We used modified NCEP-ATP III criteria to diagnose metabolic syndrome in young adolescents including: blood pressure ≧90th percentile, fasting glucose ≧90th, TG ≧ 90th, HDL-C ≦ 10th, and BMI or WC ≧ 90th according to age and gender specific recommendations. Results. The overall prevalence of MetS was 4.8% for boys and 3.9% for girls. BMI and WC were significantly associated with MetS for both boys and girls, even after adjusting for age, cigarette smoking, alcohol drinking and pubertal status. However, after further adjusting for BMI or WC, WC for boys (OR = 1.14, 95% CI = 1.05-1.24) and BMI for girls (OR = 1.36, 95% CI = 1.13-1.64) were significantly associated with MetS. Conclusions. Adolescents with abnormal BMI or waist circumference had 10 to 20 times higher odds of MetS when compared to normal subjects. Obesity, either general or central adiposity, may play an important role in the development of MetS among adolescents.
背景。评估台湾青少年中人体测量指标对代谢综合征(MetS)的患病率及其重要性。方法。我们于2003年对台北青少年进行了一项横断面调查,以获取具有代表性的样本,共纳入1562名11至15岁的青少年(764名男孩和798名女孩)。我们采用修改后的NCEP-ATP III标准来诊断青少年的代谢综合征,包括:血压≧第90百分位数、空腹血糖≧第90百分位数、甘油三酯≧第90百分位数、高密度脂蛋白胆固醇≦第10百分位数,以及根据年龄和性别特定建议的体重指数(BMI)或腰围(WC)≧第90百分位数。结果。男孩代谢综合征的总体患病率为4.8%,女孩为3.9%。无论男孩还是女孩,即使在调整了年龄、吸烟、饮酒和青春期状态后,BMI和WC与代谢综合征均显著相关。然而,在进一步调整BMI或WC后,男孩的WC(比值比[OR]=1.14,95%置信区间[CI]=1.05-1.24)和女孩的BMI(OR=1.36,95%CI=1.13-1.64)与代谢综合征显著相关。结论。与正常受试者相比,BMI或腰围异常的青少年患代谢综合征的几率高出10至20倍。肥胖,无论是全身性还是中心性肥胖,可能在青少年代谢综合征的发生发展中起重要作用。