Mahoney M C, Burnett W S, Majerovics A, Tanenbaum H
Bureau of Cancer Epidemiology, New York State Department of Health, Albany 12237-0683.
Ophthalmology. 1990 Sep;97(9):1143-7. doi: 10.1016/s0161-6420(90)32445-4.
The epidemiologic characteristics of more than 1400 primary eye cancers (ICD-9, site 190) diagnosed among New York State (NYS) residents between 1975 and 1986 are described. Among NYS male residents, the average annual age-adjusted incidence rate was 7.5 per 1,000,000, and among NYS female residents, the rate was 5.4 per 1,000,000 (male:female rate ratio, 1.39). The majority of ophthalmic malignancies were included within three histologic groupings: melanomas (70.4%), retinoblastomas (9.8%), and squamous cell carcinomas (9.2%). The average annual incidence of retinoblastoma among persons in NYS who were less than 5 years of age was 9.5 per 1,000,000 for boys and 8.7 per 1,000,000 for girls (male:female rate ratio, 1.09). The average annual incidence (age-adjusted) of ocular melanomas was 4.9 per 1,000,000 among men and 3.7 per 1,000,000 among women in NYS (male:female rate ratio, 1.32). Expanded knowledge of the epidemiology of ophthalmic cancers can help to develop a foundation on which to monitor disease patterns and can serve to stimulate further etiologic research involving these rare malignancies.
本文描述了1975年至1986年间纽约州（NYS）居民诊断出的1400多例原发性眼癌（ICD-9，部位190）的流行病学特征。在纽约州男性居民中，年龄调整后的年平均发病率为每100万人7.5例，在纽约州女性居民中，该发病率为每100万人5.4例（男：女发病率比为1.39）。大多数眼部恶性肿瘤包含在三个组织学分组中：黑色素瘤（70.4%）、视网膜母细胞瘤（9.8%）和鳞状细胞癌（9.2%）。纽约州5岁以下人群中视网膜母细胞瘤的年平均发病率，男孩为每100万人9.5例，女孩为每100万人8.7例（男：女发病率比为1.09）。纽约州男性眼部黑色素瘤的年平均发病率（年龄调整后）为每100万人4.9例，女性为每100万人3.7例（男：女发病率比为1.32）。对眼癌流行病学的进一步了解有助于建立一个监测疾病模式的基础，并有助于推动对这些罕见恶性肿瘤的病因学研究。
