Department of Dermatology, Mayo Clinic, Rochester, MN 55905, USA.
Int J Dermatol. 2012 Mar;51(3):243-9. doi: 10.1111/j.1365-4632.2011.05245.x.
Cutaneous metastases are common sequelae of primary malignant melanoma. Because patients with melanoma are examined frequently after diagnosis, it is important that dermatologists are aware of the range of findings that may represent metastatic disease. Many case reports and a few retrospective series have been published detailing the wide variety of clinical presentations of cutaneous metastatic melanoma. This article reviews the various manifestations of metastatic melanoma of the skin and oral mucous membranes and summarizes treatment options for metastatic disease.
皮肤转移是原发性恶性黑色素瘤的常见后遗症。由于黑色素瘤患者在确诊后经常接受检查,皮肤科医生了解可能代表转移性疾病的各种发现非常重要。许多病例报告和少数回顾性系列已发表,详细描述了皮肤转移性黑色素瘤的广泛临床表现。本文回顾了皮肤和口腔黏膜转移性黑色素瘤的各种表现,并总结了转移性疾病的治疗选择。